BMRB Entry 17103
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PDB ID:
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR17103
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Title: The structure of the calcium-sensitizer, dfbp-o, in complex with the N-domain of troponin C and the switch region of troponin I PubMed: 20801130
Deposition date: 2010-08-03 Original release date: 2010-09-08
Authors: Robertson, Ian; Sun, Yin-Biao; Li, Monica; Sykes, Brian
Citation: Robertson, Ian; Sun, Yin-Biao; Li, Monica; Sykes, Brian. "A structural and functional perspective into the mechanism of Ca(2+)-sensitizers that target the cardiac troponin complex." J. Mol. Cell. Cardiol. 49, 1031-1041 (2010).
Assembly members:
cNTnC, polymer, 89 residues, 10070.361 Da.
cTnI(144-163), polymer, 20 residues, 2219.711 Da.
CA, non-polymer, 40.078 Da.
dfbp-o, non-polymer, 197.239 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
cNTnC: MDDIYKAAVEQLTEEQKNEF
KAAFDIFVLGAEDGCISTKE
LGKVMRMLGQNPTPEELQEM
IDEVDEDGSGTVDFDEFLVM
MVRCMKDDS
cTnI(144-163): RRVRISADAMMQALLGARAK
- assigned_chemical_shifts
Data type | Count |
13C chemical shifts | 266 |
15N chemical shifts | 85 |
1H chemical shifts | 665 |