BMRB Entry 6268
Click here to enlarge.
            
                PDB ID: 
                
                
                Entry in NMR Restraints Grid
                Validation report in NRG-CING
            Chem Shift validation:  AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR6268
MolProbity Validation Chart            
                    NMR-STAR file interactive viewer.
                    NMR-STAR v3 text file.
                    NMR-STAR v2.1 text file (deprecated)
                    XML gzip file.
                    RDF gzip file.
                    All files associated with the entry
                
Title: CBP TAZ1 Domain PubMed: 15641773
Deposition date: 2004-07-19 Original release date: 2005-02-21
Authors: De Guzman, Roberto; Wojciak, Jonathan; Martinez-Yamout, Maria; Dyson, H. Jane; wright, Peter
Citation: De Guzman, Roberto; Wojciak, Jonathan; Martinez-Yamout, Maria; Dyson, H. Jane; Wright, Peter. "CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding" Biochemistry 44, 490-497 (2005).
Assembly members:
CBP TAZ1 domain, polymer, 100 residues,  Formula weight is not available
ZN, non-polymer,   65.409 Da.
Natural source: Common Name: Mouse Taxonomy ID: 10090 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Mus musculus
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
CBP TAZ1 domain: ATGPTADPEKRKLIQQQLVL
LLHAHKCQRREQANGEVRAC
SLPHCRTMKNVLNHMTHCQA
GKACQVAHCASSRQIISHWK
NCTRHDCPVCLPLKNASDKR
- assigned_chemical_shifts
| Data type | Count | 
| 13C chemical shifts | 284 | 
| 1H chemical shifts | 562 | 
| 15N chemical shifts | 95 | 
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID | 
|---|---|---|
| 1 | CBP TAZ1 | 1 | 
| 2 | ZINC (II) ION, 1 | 2 | 
| 3 | ZINC (II) ION, 2 | 2 | 
| 4 | ZINC (II) ION, 3 | 2 | 
Entities:
Entity 1, CBP TAZ1 100 residues - Formula weight is not available
| 1 | ALA | THR | GLY | PRO | THR | ALA | ASP | PRO | GLU | LYS | |
| 2 | ARG | LYS | LEU | ILE | GLN | GLN | GLN | LEU | VAL | LEU | |
| 3 | LEU | LEU | HIS | ALA | HIS | LYS | CYS | GLN | ARG | ARG | |
| 4 | GLU | GLN | ALA | ASN | GLY | GLU | VAL | ARG | ALA | CYS | |
| 5 | SER | LEU | PRO | HIS | CYS | ARG | THR | MET | LYS | ASN | |
| 6 | VAL | LEU | ASN | HIS | MET | THR | HIS | CYS | GLN | ALA | |
| 7 | GLY | LYS | ALA | CYS | GLN | VAL | ALA | HIS | CYS | ALA | |
| 8 | SER | SER | ARG | GLN | ILE | ILE | SER | HIS | TRP | LYS | |
| 9 | ASN | CYS | THR | ARG | HIS | ASP | CYS | PRO | VAL | CYS | |
| 10 | LEU | PRO | LEU | LYS | ASN | ALA | SER | ASP | LYS | ARG | 
Entity 2, ZINC (II) ION, 1 - Zn - 65.409 Da.
| 1 | ZN | 
Samples:
sample_1: CBP TAZ1 domain, [U-13C; U-15N], 1 mM; Tris 10 mM; NaCl 50 mM; DTT 2 mM
sample_2: CBP TAZ1 domain, [U-15N], 1 mM; Tris 10 mM; NaCl 50 mM; DTT 2 mM
Ex-cond_1: pH: 6.9; temperature: 298 K
Experiments:
| Name | Sample | Sample state | Sample conditions | 
|---|---|---|---|
| 1H15N_HSQC | not available | not available | Ex-cond_1 | 
Software:
No software information available
NMR spectrometers:
- Bruker DRX 600 MHz
- Bruker DRX 800 MHz
- Bruker Avance 900 MHz
Related Database Links:
| SP | Q92793 P45481 | 
| REF | NP_596872 NP_004371 NP_001157494 NP_001073315 NP_001020603 | 
| PRF | 1923401A | 
| GB | AAH72594 AAC51770 AAC51331 AAC08447 AAB28651 | 
| DBJ | BAI45616 BAG65526 BAE06125 | 
| PDB | |
| BMRB | 5987 5327 16014 | 
Download simulated HSQC data in one of the following formats:
            
CSV: Backbone
            or all simulated shifts
            
SPARKY: Backbone
            or all simulated shifts
    
