BMRB Entry 30210
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PDB ID:
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR30210
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Title: Solution structure of the zinc fingers 1 and 2 of MBNL1 in complex with human cardiac troponin T pre-mRNA PubMed: 28718627
Deposition date: 2016-12-15 Original release date: 2017-07-25
Authors: Phukan, P.; Park, S.; Martinez-Yamout, M.; Zeeb, M.; Dyson, H.; Wright, P.
Citation: Park, Sangho; Phukan, Priti Deka; Zeeb, Markus; Martinez-Yamout, Maria; Dyson, Helen Jane; Wright, Peter. "Structural basis for interaction of the tandem zinc finger domains of human muscleblind with cognate RNA from human cardiac troponin T" Biochemistry 56, 4154-4168 (2017).
Assembly members:
Muscleblind-like protein 1, polymer, 92 residues, 10577.180 Da.
RNA (5'-R(P*GP*UP*CP*UP*CP*GP*CP*UP*UP*UP*UP*CP*CP*CP*C)-3'), polymer, 15 residues, 4618.721 Da.
ZINC ION, non-polymer, 65.409 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
Muscleblind-like protein 1: MAVSVTPIRDTKWLTLEVCR
EFQRGTCSRPDTECKFAHPS
KSCQVENGRVIACFDSLKGR
CSRENCKYLHPPPHLKTQLE
INGRNNLIQQKN
RNA (5'-R(P*GP*UP*CP*UP*CP*GP*CP*UP*UP*UP*UP*CP*CP*CP*C)-3'): GUCUCGCUUUUCCCC
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 300 |
| 15N chemical shifts | 85 |
| 1H chemical shifts | 554 |