data_15464 ####################### # Entry information # ####################### save_entry_information _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information _Entry.ID 15464 _Entry.Title ; NMR STRUCTURE OF HUMAN INSULIN MONOMER IN 35% CD3CN ZINC FREE, 50 STRUCTURES ; _Entry.Type macromolecule _Entry.Version_type original _Entry.Submission_date 2007-09-11 _Entry.Accession_date 2007-09-11 _Entry.Last_release_date . _Entry.Original_release_date . _Entry.Origination author _Entry.NMR_STAR_version 3.1.1.61 _Entry.Original_NMR_STAR_version 3.0.8.100 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype solution _Entry.Details . _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.Entry_ID 1 Wojciech Bocian . . . 15464 2 Lech Kozerski . . . 15464 stop_ loop_ _SG_project.SG_project_ID _SG_project.Project_name _SG_project.Full_name_of_center _SG_project.Initial_of_center _SG_project.Entry_ID 1 'not applicable' 'Accelerated Technologies Center for Gene to 3D Structure' . 15464 stop_ loop_ _Struct_keywords.Keywords _Struct_keywords.Text _Struct_keywords.Entry_ID '35% CD3CN' . 15464 'Human Insulin' . 15464 Monomer . 15464 NMR . 15464 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID assigned_chemical_shifts 1 15464 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID '1H chemical shifts' 339 15464 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 2 . . 2010-05-26 2007-09-11 update BMRB 'update entity name' 15464 1 . . 2008-06-25 2007-09-11 original author 'original release' 15464 stop_ loop_ _Related_entries.Database_name _Related_entries.Database_accession_code _Related_entries.Relationship _Related_entries.Entry_ID PDB 2JV1 'BMRB Entry Tracking System' 15464 stop_ save_ ############### # Citations # ############### save_entry_citation _Citation.Sf_category citations _Citation.Sf_framecode entry_citation _Citation.Entry_ID 15464 _Citation.ID 1 _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code . _Citation.DOI . _Citation.PubMed_ID 18040865 _Citation.Full_citation . _Citation.Title 'Structure of human insulin monomer in water/acetonitrile solution' _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'J. Biomol. NMR' _Citation.Journal_name_full . _Citation.Journal_volume 40 _Citation.Journal_issue 1 _Citation.Journal_ASTM . _Citation.Journal_ISSN . _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 55 _Citation.Page_last 64 _Citation.Year 2008 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.Entry_ID _Citation_author.Citation_ID 1 Wojciech Bocian . . . 15464 1 2 Jerzy Sitkowski . . . 15464 1 3 Elzbieta Bednarek . . . 15464 1 4 Anna Tarnowska . . . 15464 1 5 Robert Kawecki . . . 15464 1 6 Lech Kozerski . . . 15464 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_assembly _Assembly.Sf_category assembly _Assembly.Sf_framecode assembly _Assembly.Entry_ID 15464 _Assembly.ID 1 _Assembly.Name 'Human Insulin Monomer' _Assembly.BMRB_code . _Assembly.Number_of_components 2 _Assembly.Organic_ligands . _Assembly.Metal_ions . _Assembly.Non_standard_bonds . _Assembly.Ambiguous_conformational_states . _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange . _Assembly.Paramagnetic no _Assembly.Thiol_state . _Assembly.Molecular_mass . _Assembly.Enzyme_commission_number . _Assembly.Details . _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 'chain A' 1 $entity_1 A . yes native no no . . . 15464 1 2 'chain B' 2 $entity_2 B . yes native no no . . . 15464 1 stop_ loop_ _Bond.ID _Bond.Type _Bond.Value_order _Bond.Assembly_atom_ID_1 _Bond.Entity_assembly_ID_1 _Bond.Entity_assembly_name_1 _Bond.Entity_ID_1 _Bond.Comp_ID_1 _Bond.Comp_index_ID_1 _Bond.Seq_ID_1 _Bond.Atom_ID_1 _Bond.Assembly_atom_ID_2 _Bond.Entity_assembly_ID_2 _Bond.Entity_assembly_name_2 _Bond.Entity_ID_2 _Bond.Comp_ID_2 _Bond.Comp_index_ID_2 _Bond.Seq_ID_2 _Bond.Atom_ID_2 _Bond.Auth_entity_assembly_ID_1 _Bond.Auth_entity_assembly_name_1 _Bond.Auth_seq_ID_1 _Bond.Auth_comp_ID_1 _Bond.Auth_atom_ID_1 _Bond.Auth_entity_assembly_ID_2 _Bond.Auth_entity_assembly_name_2 _Bond.Auth_seq_ID_2 _Bond.Auth_comp_ID_2 _Bond.Auth_atom_ID_2 _Bond.Entry_ID _Bond.Assembly_ID 1 disulfide single . 1 entity_1 1 CYS 6 6 SG . 1 entity_1 1 CYS 11 11 SG . . . . . . . . . . 15464 1 2 disulfide single . 1 entity_1 1 CYS 7 7 SG . 2 entity_2 2 CYS 7 7 SG . . . . . . . . . . 15464 1 3 disulfide single . 1 entity_1 1 CYS 20 20 SG . 2 entity_2 2 CYS 19 19 SG . . . . . . . . . . 15464 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_entity_1 _Entity.Sf_category entity _Entity.Sf_framecode entity_1 _Entity.Entry_ID 15464 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name 'chain A' _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID A _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; GIVEQCCTSICSLYQLENYC N ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 21 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'all disulfide bound' _Entity.Src_method man _Entity.Parent_entity_ID 1 _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight 2383.700 _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date 2015-11-26 loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID 1 no BMRB 1000 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 2 no BMRB 1002 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 3 no BMRB 1004 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 4 no BMRB 1006 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 5 no BMRB 1008 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 6 no BMRB 1010 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 7 no BMRB 1012 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 8 no BMRB 1014 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 9 no BMRB 1016 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 10 no BMRB 1018 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 11 no BMRB 1020 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 12 no BMRB 1022 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 13 no BMRB 1023 . "insulin B chain" . . . . . 95.24 42 100.00 100.00 1.05e-03 . . . . 15464 1 14 no BMRB 11016 . "Chain A" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 15 no BMRB 1344 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 16 no BMRB 1585 . "insulin A chain" . . . . . 95.24 21 100.00 100.00 1.28e-03 . . . . 15464 1 17 no BMRB 1587 . "insulin A chain" . . . . . 95.24 21 100.00 100.00 1.28e-03 . . . . 15464 1 18 no BMRB 16026 . INSULIN_A_CHAIN . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 19 no BMRB 16027 . INSULIN_A_CHAIN . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 20 no BMRB 1632 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 21 no BMRB 16343 . INSULIN_A_CHAIN . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 22 no BMRB 16608 . Proinsulin . . . . . 100.00 86 100.00 100.00 5.99e-05 . . . . 15464 1 23 no BMRB 16663 . "entity, chain 1" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 24 no BMRB 16915 . "entity, chain 1" . . . . . 100.00 22 100.00 100.00 1.61e-04 . . . . 15464 1 25 no BMRB 17107 . entity_1 . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 26 no BMRB 1761 . "insulin A chain" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 27 no BMRB 17803 . "InsulinGR 1" . . . . . 100.00 22 100.00 100.00 1.61e-04 . . . . 15464 1 28 no BMRB 18858 . entity_1 . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 29 no BMRB 18859 . entity_1 . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 30 no BMRB 18921 . chain_A . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 31 no BMRB 18923 . chain_A . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 32 no BMRB 18924 . chain_A . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 33 no BMRB 18925 . chain_A . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 34 no BMRB 19822 . entity_1 . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 35 no BMRB 19978 . entity_1 . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 36 no BMRB 19979 . entity . . . . . 100.00 51 100.00 100.00 1.21e-04 . . . . 15464 1 37 no BMRB 20052 . Human_Insulin_A-chain_peptide . . . . . 71.43 15 100.00 100.00 4.56e+00 . . . . 15464 1 38 no BMRB 20053 . Insulin_A-chain_variant_peptide . . . . . 71.43 17 100.00 100.00 3.29e+00 . . . . 15464 1 39 no BMRB 25260 . entity_1 . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 40 no BMRB 25261 . entity_1 . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 41 no BMRB 4266 . [D-AlaB26]destetra(B27-B30)insulin-B26-amide . . . . . 100.00 47 100.00 100.00 1.07e-04 . . . . 15464 1 42 no PDB 1A7F . "Insulin Mutant B16 Glu, B24 Gly, Des-B30, Nmr, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 43 no PDB 1AI0 . "R6 Human Insulin Hexamer (Non-Symmetric), Nmr, 10 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 44 no PDB 1AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 10 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 45 no PDB 1B17 . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 5.00 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 46 no PDB 1B18 . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 5.53 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 47 no PDB 1B19 . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 5.80 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 48 no PDB 1B2A . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.00 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 49 no PDB 1B2B . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.16 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 50 no PDB 1B2C . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.26 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 51 no PDB 1B2D . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.35 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 52 no PDB 1B2E . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.50 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 53 no PDB 1B2F . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.98 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 54 no PDB 1B2G . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 9.00 Coordinates)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 55 no PDB 1B9E . "Human Insulin Mutant Serb9glu" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 56 no PDB 1BEN . "Insulin Complexed With 4-Hydroxybenzamide" . . . . . 95.24 21 100.00 100.00 1.28e-03 . . . . 15464 1 57 no PDB 1BZV . "[d-Alab26]-Des(B27-B30)-Insulin-B26-Amide A Superpotent Single-Replacement Insulin Analogue, Nmr, Minimized Average Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 58 no PDB 1DEI . "Desheptapeptide (B24-B30) Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 59 no PDB 1EFE . "An Active Mini-Proinsulin, M2pi" . . . . . 100.00 60 100.00 100.00 8.68e-05 . . . . 15464 1 60 no PDB 1EV3 . "Structure Of The Rhombohedral Form Of The M-cresol/insulin R6 Hexamer" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 61 no PDB 1EV6 . "Structure Of The Monoclinic Form Of The M-CresolINSULIN R6 Hexamer" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 62 no PDB 1EVR . "The Structure Of The ResorcinolINSULIN R6 HEXAMER" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 63 no PDB 1FU2 . "First Protein Structure Determined From X-Ray Powder Diffraction Data" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 64 no PDB 1FUB . "First Protein Structure Determined From X-Ray Powder Diffraction Data" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 65 no PDB 1G7A . "1.2 A Structure Of T3r3 Human Insulin At 100 K" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 66 no PDB 1G7B . "1.3 A Structure Of T3r3 Human Insulin At 100 K" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 67 no PDB 1GUJ . "Insulin At Ph 2: Structural Analysis Of The Conditions Promoting Insulin Fibre Formation." . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 68 no PDB 1HIQ . "Paradoxical Structure And Function In A Mutant Human Insulin Associated With Diabetes Mellitus" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 69 no PDB 1HIS . "Structure And Dynamics Of Des-Pentapeptide-Insulin In Solution: The Molten-Globule Hypothesis." . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 70 no PDB 1HIT . "Receptor Binding Redefined By A Structural Switch In A Mutant Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 71 no PDB 1HLS . "Nmr Structure Of The Human Insulin-His(B16)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 72 no PDB 1HTV . "Crystal Structure Of Destripeptide (B28-B30) Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 73 no PDB 1HUI . "Insulin Mutant (B1, B10, B16, B27)glu, Des-B30, Nmr, 25 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 74 no PDB 1IZA . "Role Of B13 Glu In Insulin Assembly: The Hexamer Structure Of Recombinant Mutant (B13 Glu-> Gln) Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 75 no PDB 1IZB . "Role Of B13 Glu In Insulin Assembly: The Hexamer Structure Of Recombinant Mutant (B13 Glu-> Gln) Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 76 no PDB 1JCO . "Solution Structure Of The Monomeric [thr(B27)->pro,Pro(B28)- >thr] Insulin Mutant (Pt Insulin)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 77 no PDB 1LPH . "Lys(B28)pro(B29)-Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 78 no PDB 1M5A . "Crystal Structure Of 2-Co(2+)-Insulin At 1.2a Resolution" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 79 no PDB 1MHI . "Three-Dimensional Solution Structure Of An Insulin Dimer. A Study Of The B9(Asp) Mutant Of Human Insulin Using Nuclear Magnetic" . . . . . 95.24 21 100.00 100.00 1.28e-03 . . . . 15464 1 80 no PDB 1MHJ . "Solution Structure Of The Superactive Monomeric Des- [phe(B25)] Human Insulin Mutant. Elucidation Of The Structural Basis For T" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 81 no PDB 1MPJ . "X-Ray Crystallographic Studies On Hexameric Insulins In The Presence Of Helix-Stabilizing Agents, Thiocyanate, Methylparaben An" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 82 no PDB 1MSO . "T6 Human Insulin At 1.0 A Resolution" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 83 no PDB 1OS3 . "Dehydrated T6 Human Insulin At 100 K" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 84 no PDB 1OS4 . "Dehydrated T6 Human Insulin At 295 K" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 85 no PDB 1QIY . "Human Insulin Hexamers With Chain B His Mutated To Tyr Complexed With Phenol" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 86 no PDB 1QIZ . "Human Insulin Hexamers With Chain B His Mutated To Tyr Complexed With Resorcinol" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 87 no PDB 1QJ0 . "Human Insulin Hexamers With Chain B His Mutated To Tyr" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 88 no PDB 1SDB . "Porcine Desb1-2 Despentapeptide(B26-B30) Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 89 no PDB 1SF1 . "Nmr Structure Of Human Insulin Under Amyloidogenic Condition, 15 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 90 no PDB 1SJT . "Mini-Proinsulin, Two Chain Insulin Analog Mutant: Des B30, His(B 10)asp, Pro(B 28)asp, Nmr, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 91 no PDB 1SJU . "Mini-Proinsulin, Single Chain Insulin Analog Mutant: Des B30, His(B 10)asp, Pro(B 28)asp And Peptide Bond Between Lys B 29 And " . . . . . 100.00 50 100.00 100.00 1.15e-04 . . . . 15464 1 92 no PDB 1T1K . "Nmr Structure Of Human Insulin Mutant His-B10-Asp, Val-B12- Ala, Pro-B28-Lys, Lys-B29-Pro, 15 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 93 no PDB 1T1P . "Nmr Structure Of Human Insulin Mutant His-B10-Asp, Val-B12- Thr, Pro-B28-Lys, Lys-B29-Pro, 15 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 94 no PDB 1T1Q . "Nmr Structure Of Human Insulin Mutant His-B10-Asp, Val-B12-Aba, Pro- B28-Lys, Lys-B29-Pro, 15 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 95 no PDB 1TRZ . "Crystallographic Evidence For Dual Coordination Around Zinc In The T3r3 Human Insulin Hexamer" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 96 no PDB 1TYL . "The Structure Of A Complex Of Hexameric Insulin And 4'- Hydroxyacetanilide" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 97 no PDB 1TYM . "The Structure Of A Complex Of Hexameric Insulin And 4'- Hydroxyacetanilide" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 98 no PDB 1UZ9 . "Crystallographic And Solution Studies Of N-Lithocholyl Insulin: A New Generation Of Prolonged-Acting Insulins." . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 99 no PDB 1W8P . "Structural Properties Of The B25tyr-Nme-B26phe Insulin Mutant." . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 100 no PDB 1WAV . "Crystal Structure Of Form B Monoclinic Crystal Of Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 101 no PDB 1XDA . "Structure Of Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 102 no PDB 1XGL . "Human Insulin Disulfide Isomer, Nmr, 10 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 103 no PDB 1ZEG . "Structure Of B28 Asp Insulin In Complex With Phenol" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 104 no PDB 1ZEH . "Structure Of Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 105 no PDB 1ZEI . "Cross-Linked B28 Asp Insulin" . . . . . 100.00 53 100.00 100.00 8.42e-05 . . . . 15464 1 106 no PDB 1ZNI . Insulin . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 107 no PDB 1ZNJ . "Insulin, Monoclinic Crystal Form" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 108 no PDB 2AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 109 no PDB 2C8Q . "Insuline(1sec) And Uv Laser Excited Fluorescence" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 110 no PDB 2C8R . "Insuline(60sec) And Uv Laser Excited Fluorescence" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 111 no PDB 2CEU . "Despentapeptide Insulin In Acetic Acid (Ph 2)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 112 no PDB 2EFA . "Neutron Crystal Structure Of Cubic Insulin At Pd6.6" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 113 no PDB 2G4M . "Insulin Collected At 2.0 A Wavelength" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 114 no PDB 2H67 . "Nmr Structure Of Human Insulin Mutant His-B5-Ala, His-B10- Asp Pro-B28-Lys, Lys-B29-Pro, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 115 no PDB 2HH4 . "Nmr Structure Of Human Insulin Mutant Gly-B8-D-Ser, His-B10- Asp Pro-B28-Lys, Lys-B29-Pro, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 116 no PDB 2HHO . "Nmr Structure Of Human Insulin Mutant Gly-B8-Ser, His-B10- Asp Pro-B28-Lys, Lys-B29-Pro, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 117 no PDB 2HIU . "Nmr Structure Of Human Insulin In 20% Acetic Acid, Zinc- Free, 10 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 118 no PDB 2JMN . "Nmr Structure Of Human Insulin Mutant His-B10-Asp, Pro-B28- Lys, Lys-B29-Pro, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 119 no PDB 2JV1 . "Nmr Structure Of Human Insulin Monomer In 35% Cd3cn Zinc Free, 50 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 120 no PDB 2K91 . "Enhancing The Activity Of Insulin By Stereospecific Unfolding" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 121 no PDB 2K9R . "Enhancing The Activity Of Insulin By Stereospecific Unfolding" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 122 no PDB 2KJJ . "Dynamics Of Insulin Probed By 1h-Nmr Amide Proton Exchange A Flexibility Of The Receptor-Binding Surface" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 123 no PDB 2KJU . "Nmr Structure Of Human Insulin Mutant Glu-B21-D-Glu, His-B10 B28-Lys, Lys-B29-Pro, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 124 no PDB 2KQP . "Nmr Structure Of Proinsulin" . . . . . 100.00 86 100.00 100.00 5.99e-05 . . . . 15464 1 125 no PDB 2KQQ . "Nmr Structure Of Human Insulin Mutant Gly-B8-D-Ala, His-B10-Asp, Pro- B28-Lys, Lys-B29-Pro, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 126 no PDB 2KXK . "Human Insulin Mutant A22gly-B31lys-B32arg" . . . . . 100.00 22 100.00 100.00 1.61e-04 . . . . 15464 1 127 no PDB 2L1Y . "Nmr Structure Of Human Insulin Mutant Gly-B20-D-Ala, Gly-B23-D-Ala Pro-B28-Lys, Lys-B29-Pro, 20 Structures" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 128 no PDB 2LGB . "Modified A22gly-B31arg Human Insulin" . . . . . 100.00 22 100.00 100.00 1.61e-04 . . . . 15464 1 129 no PDB 2M1D . "Biosynthetic Engineered B28k-b29p Human Insulin Monomer Structure In In Water/acetonitrile Solutions." . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 130 no PDB 2M1E . "Biosynthetic Engineered B28k-b29p Human Insulin Monomer Structure In In Water Solutions." . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 131 no PDB 2M2M . "Structure Of [l-hisb24] Insulin Analogue At Ph 1.9" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 132 no PDB 2M2N . "Structure Of [l-hisb24] Insulin Analogue At Ph 8.0" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 133 no PDB 2M2O . "Structure Of [d-hisb24] Insulin Analogue At Ph 1.9" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 134 no PDB 2M2P . "Structure Of [d-hisb24] Insulin Analogue At Ph 8.0" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 135 no PDB 2MLI . "Nmr Structure Of B25-(alpha, Beta)-dehydro-phenylalanine Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 136 no PDB 2MPG . "Solution Structure Of The [aibb8,lysb28,prob29]-insulin Analogue" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 137 no PDB 2MVC . "Solution Structure Of Human Insulin At Ph 1.9" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 138 no PDB 2MVD . "Solution Structure Of [glnb22]-insulin Mutant At Ph 1.9" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 139 no PDB 2OLY . "Structure Of Human Insulin In Presence Of Urea At Ph 7.0" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 140 no PDB 2OLZ . "Structure Of Human Insulin In Presence Of Thiocyanate At Ph 7.0" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 141 no PDB 2OM0 . "Structure Of Human Insulin In Presence Of Urea At Ph 6.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 142 no PDB 2OM1 . "Structure Of Human Insulin In Presence Of Thiocyanate At Ph 6.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 143 no PDB 2OMG . "Structure Of Human Insulin Cocrystallized With Protamine And Urea" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 144 no PDB 2OMH . "Structure Of Human Insulin Cocrystallized With Arg-12 Peptide In Presence Of Urea" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 145 no PDB 2OMI . "Structure Of Human Insulin Cocrystallized With Protamine" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 146 no PDB 2QIU . "Structure Of Human Arg-Insulin" . . . . . 100.00 22 100.00 100.00 1.33e-04 . . . . 15464 1 147 no PDB 2R34 . "Crystal Structure Of Mn Human Arg-Insulin" . . . . . 100.00 22 100.00 100.00 1.33e-04 . . . . 15464 1 148 no PDB 2R35 . "Crystal Structure Of Rb Human Arg-Insulin" . . . . . 100.00 22 100.00 100.00 1.33e-04 . . . . 15464 1 149 no PDB 2R36 . "Crystal Structure Of Ni Human Arg-Insulin" . . . . . 100.00 22 100.00 100.00 1.33e-04 . . . . 15464 1 150 no PDB 2RN5 . "Humal Insulin Mutant B31lys-B32arg" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 151 no PDB 2TCI . "X-Ray Crystallographic Studies On Hexameric Insulins In The Presence Of Helix-Stabilizing Agents, Thiocyanate, Methylparaben An" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 152 no PDB 2VJZ . "Crystal Structure Form Ultalente Insulin Microcrystals" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 153 no PDB 2VK0 . "Crystal Structure Form Ultalente Insulin Microcrystals" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 154 no PDB 2W44 . "Structure Deltaa1-a4 Insulin" . . . . . 80.95 17 100.00 100.00 1.24e-01 . . . . 15464 1 155 no PDB 2WBY . "Crystal Structure Of Human Insulin-Degrading Enzyme In Complex With Insulin" . . . . . 95.24 20 100.00 100.00 9.42e-04 . . . . 15464 1 156 no PDB 2WC0 . "Crystal Structure Of Human Insulin Degrading Enzyme In Complex With Iodinated Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 157 no PDB 2WRU . "Semi-synthetic Highly Active Analogue Of Human Insulin Nmealab26-dti-nh2" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 158 no PDB 2WRV . "Semi-Synthetic Highly Active Analogue Of Human Insulin Nmehisb26-Dti-Nh2" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 159 no PDB 2WRW . "Semi-Synthetic Highly Active Analogue Of Human Insulin D- Prob26-Dti-Nh2" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 160 no PDB 2WRX . "Semi-Synthetic Analogue Of Human Insulin Nmealab26-Insulin At Ph 3.0" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 161 no PDB 2WS0 . "Semi-Synthetic Analogue Of Human Insulin Nmealab26-Insulin At Ph 7.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 162 no PDB 2WS1 . "Semi-Synthetic Analogue Of Human Insulin Nmetyrb26-Insulin In Monomer Form" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 163 no PDB 2WS4 . "Semi-Synthetic Analogue Of Human Insulin Prob26-Dti In Monomer Form" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 164 no PDB 2WS6 . "Semi-Synthetic Analogue Of Human Insulin Nmetyrb26-Insulin In Hexamer Form" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 165 no PDB 2WS7 . "Semi-Synthetic Analogue Of Human Insulin Prob26-Dti" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 166 no PDB 2ZPP . "Neutron Crystal Structure Of Cubic Insulin At Pd9" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 167 no PDB 3AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, Refined Average Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 168 no PDB 3BXQ . "The Structure Of A Mutant Insulin Uncouples Receptor Binding From Protein Allostery. An Electrostatic Block To The Tr Transitio" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 169 no PDB 3E7Y . "Structure Of Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 170 no PDB 3E7Z . "Structure Of Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 171 no PDB 3EXX . "Structure Of The T6 Human Insulin Derivative With Nickel At 1.35 A Resolution" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 172 no PDB 3FHP . "A Neutron Crystallographic Analysis Of A Porcine 2zn Insulin At 2.0 A Resolution" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 173 no PDB 3I3Z . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 174 no PDB 3I40 . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 175 no PDB 3ILG . "Crystal Structure Of Humnan Insulin Sr+2 Complex" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 176 no PDB 3INC . "Crystal Structure Of Human Insulin With Ni+2 Complex" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 177 no PDB 3INS . "Structure Of Insulin. Results Of Joint Neutron And X-ray Refinement" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 178 no PDB 3IR0 . "Crystal Structure Of Human Insulin Complexed With Cu+2 Metal Ion" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 179 no PDB 3JSD . "Insulin's Biosynthesis And Activity Have Opposing Structural Requirements: A New Factor In Neonatal Diabetes Mellitus" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 180 no PDB 3MTH . "X-Ray Crystallographic Studies On Hexameric Insulins In The Presence Of Helix-Stabilizing Agents, Thiocyanate, Methylparaben An" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 181 no PDB 3P2X . "Insulin Fibrillation Is The Janus Face Of Induced Fit. A Chiaral Clamp Stabilizes The Native State At The Expense Of Activity" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 182 no PDB 3P33 . "Insulin Fibrillation Is The Janus Face Of Induced Fit. A Chiral Clamp Stabilizes The Native State At The Expense Of Activity" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 183 no PDB 3Q6E . "Human Insulin In Complex With Cucurbit[7]uril" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 184 no PDB 3ROV . "Insulin's Biosynthesis And Activity Have Opposing Structural Requirements: A New Factor In Neonatal Diabetes Mellitus" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 185 no PDB 3RTO . "Acoustically Mounted Porcine Insulin Microcrystals Yield An X-Ray Sad Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 186 no PDB 3T2A . "Tmao-Grown Cubic Insulin (Porcine)" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 187 no PDB 3TT8 . "Crystal Structure Analysis Of Cu Human Insulin Derivative" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 188 no PDB 3U4N . "A Novel Covalently Linked Insulin Dimer" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 189 no PDB 3V1G . "Forestalling Insulin Fibrillation By Insertion Of A Chiral Clamp Mechanism-Based Application Of Protein Engineering To Global H" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 190 no PDB 3W11 . "Insulin Receptor Ectodomain Construct Comprising Domains L1-cr In Complex With Human Insulin, Alpha-ct Peptide(704-719) And Fab" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 191 no PDB 3W12 . "Insulin Receptor Ectodomain Construct Comprising Domains L1-cr In Complex With High-affinity Insulin Analogue [d-pro-b26]-dti-n" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 192 no PDB 3W13 . "Insulin Receptor Ectodomain Construct Comprising Domains L1-cr In Complex With High-affinity Insulin Analogue [d-pro-b26]-dti-n" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 193 no PDB 3W7Y . "0.92a Structure Of 2zn Human Insulin At 100k" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 194 no PDB 3W7Z . "1.15a Structure Of Human 2zn Insulin At 293k" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 195 no PDB 3W80 . "Crystal Structure Of Dodecamer Human Insulin With Double C-axis Length Of The Hexamer 2 Zn Insulin Cell" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 196 no PDB 3ZI3 . "Crystal Structure Of The B24his-insulin - Human Analogue" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 197 no PDB 3ZQR . "Nmepheb25 Insulin Analogue Crystal Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 198 no PDB 3ZS2 . "Tyrb25,Nmepheb26,Lysb28,Prob29-Insulin Analogue Crystal Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 199 no PDB 3ZU1 . "Structure Of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 200 no PDB 4A7E . "X-Ray Crystal Structure Of Porcine Insulin Flash-Cooled At High Pressure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 201 no PDB 4AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 'green' Substate, Average Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 202 no PDB 4AJX . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 203 no PDB 4AJZ . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 204 no PDB 4AK0 . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 205 no PDB 4AKJ . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 206 no PDB 4CXL . "Human Insulin Analogue (d-prob8)-insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 207 no PDB 4CXN . "Crystal Structure Of Human Insulin Analogue (nme-alab8)- Insulin Crystal Form I" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 208 no PDB 4CY7 . "Crystal Structure Of Human Insulin Analogue (nme-alab8)- Insulin Crystal Form Ii" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 209 no PDB 4EWW . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 210 no PDB 4EWX . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 211 no PDB 4EWZ . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 212 no PDB 4EX0 . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 213 no PDB 4EX1 . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 214 no PDB 4EXX . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 215 no PDB 4EY1 . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 216 no PDB 4EY9 . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 217 no PDB 4EYD . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 218 no PDB 4EYN . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 219 no PDB 4EYP . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 220 no PDB 4F0N . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 221 no PDB 4F0O . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 222 no PDB 4F1A . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 223 no PDB 4F1B . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 224 no PDB 4F1C . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 225 no PDB 4F1D . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 226 no PDB 4F1F . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 227 no PDB 4F1G . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 228 no PDB 4F4T . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 229 no PDB 4F4V . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 230 no PDB 4F51 . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 231 no PDB 4F8F . "Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 232 no PDB 4FG3 . "Crystal Structure Analysis Of The Human Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 233 no PDB 4FKA . "High Resolution Structure Of The Manganese Derivative Of Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 234 no PDB 4GBC . "Crystal Structure Of Aspart Insulin At Ph 6.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 235 no PDB 4GBI . "Crystal Structure Of Aspart Insulin At Ph 6.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 236 no PDB 4GBK . "Crystal Structure Of Aspart Insulin At Ph 8.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 237 no PDB 4GBL . "Crystal Structure Of Aspart Insulin At Ph 8.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 238 no PDB 4GBN . "Crystal Structure Of Aspart Insulin At Ph 6.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 239 no PDB 4INS . "The Structure Of 2zn Pig Insulin Crystals At 1.5 Angstroms Resolution" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 240 no PDB 4IUZ . "High Resolution Crystal Structure Of Racemic Ester Insulin" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 241 no PDB 4NIB . "Crystal Structure Of Human Insulin Mutant B20 D-ala, B23 D-ala" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 242 no PDB 4OGA . "Insulin In Complex With Site 1 Of The Human Insulin Receptor" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 243 no PDB 4P65 . "Crystal Structure Of An Cyclohexylalanine Substituted Insulin Analog." . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 244 no PDB 4Q5Z . "Crystal Structure Analysis Of Fab-bound Human Insulin Degrading Enzyme (ide) In Complex With Insulin" . . . . . 95.24 20 100.00 100.00 9.42e-04 . . . . 15464 1 245 no PDB 4RXW . "Crystal Structure Of The Cobalt Human Insulin Derivative" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 246 no PDB 4UNE . "Human Insulin B26phe Mutant Crystal Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 247 no PDB 4UNG . "Human Insulin B26asn Mutant Crystal Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 248 no PDB 4UNH . "Human Insulin B26gly Mutant Crystal Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 249 no PDB 4XC4 . "Insulin Co-crystallizes In The Presence Of It Beta-cell Chaperone Sulfatide" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 250 no PDB 5AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 'red' Substate, Average Structure" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 251 no PDB 5CNY . "Crystal Structure Of Human Zinc Insulin At Ph 5.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 252 no PDB 5CO2 . "Crystalization Of Human Zinc Insulin At Ph 5.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 253 no PDB 5CO6 . "Crystal Structure Of Human Zinc Insulin At Ph 6.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 254 no PDB 5CO9 . "Crystal Structure Of Human Zinc Insulin At Ph 6.5" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 255 no PDB 6INS . "X-Ray Analysis Of The Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue" . . . . . 100.00 50 100.00 100.00 1.15e-04 . . . . 15464 1 256 no PDB 7INS . "Structure Of Porcine Insulin Cocrystallized With Clupeine Z" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 257 no PDB 9INS . "Monovalent Cation Binding In Cubic Insulin Crystals" . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 258 no DBJ BAH59081 . "human M-proinsulin [synthetic construct]" . . . . . 100.00 87 100.00 100.00 5.68e-05 . . . . 15464 1 259 no DBJ BAJ17943 . "insulin [synthetic construct]" . . . . . 100.00 110 100.00 100.00 5.75e-05 . . . . 15464 1 260 no DBJ BAM29044 . "insulin, partial [Suncus murinus]" . . . . . 100.00 77 100.00 100.00 4.41e-05 . . . . 15464 1 261 no EMBL CAA23424 . "unnamed protein product [synthetic construct]" . . . . . 100.00 87 100.00 100.00 5.68e-05 . . . . 15464 1 262 no EMBL CAA23475 . "preproinsulin [Canis sp.]" . . . . . 100.00 110 100.00 100.00 3.91e-05 . . . . 15464 1 263 no EMBL CAA23828 . "preproinsulin [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 5.75e-05 . . . . 15464 1 264 no EMBL CAA43403 . "Preproinsulin [Pan troglodytes]" . . . . . 100.00 110 100.00 100.00 3.57e-05 . . . . 15464 1 265 no EMBL CAA43405 . "Preproinsulin [Chlorocebus aethiops]" . . . . . 100.00 110 100.00 100.00 3.91e-05 . . . . 15464 1 266 no GB AAA17540 . "insulin, partial [Oryctolagus cuniculus]" . . . . . 100.00 55 100.00 100.00 4.30e-05 . . . . 15464 1 267 no GB AAA19033 . "insulin [Oryctolagus cuniculus]" . . . . . 100.00 110 100.00 100.00 3.87e-05 . . . . 15464 1 268 no GB AAA36849 . "preproinsulin [Macaca fascicularis]" . . . . . 100.00 110 100.00 100.00 3.68e-05 . . . . 15464 1 269 no GB AAA59172 . "insulin [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 5.75e-05 . . . . 15464 1 270 no GB AAA59173 . "insulin [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 5.75e-05 . . . . 15464 1 271 no PRF 0601246A . insulin,prepro . . . . . 100.00 110 100.00 100.00 5.75e-05 . . . . 15464 1 272 no PRF 1006230A . insulin,pro- . . . . . 100.00 86 100.00 100.00 5.63e-05 . . . . 15464 1 273 no PRF 550086A . insulin . . . . . 100.00 51 100.00 100.00 1.04e-04 . . . . 15464 1 274 no PRF 560164B . insulin . . . . . 100.00 21 100.00 100.00 1.52e-04 . . . . 15464 1 275 no PRF 580107B . insulin . . . . . 100.00 50 100.00 100.00 9.91e-05 . . . . 15464 1 276 no REF NP_000198 . "insulin preproprotein [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 5.75e-05 . . . . 15464 1 277 no REF NP_001008996 . "insulin preproprotein [Pan troglodytes]" . . . . . 100.00 110 100.00 100.00 3.57e-05 . . . . 15464 1 278 no REF NP_001075804 . "insulin precursor [Oryctolagus cuniculus]" . . . . . 100.00 110 100.00 100.00 3.87e-05 . . . . 15464 1 279 no REF NP_001103242 . "insulin precursor [Sus scrofa]" . . . . . 100.00 108 100.00 100.00 5.54e-05 . . . . 15464 1 280 no REF NP_001123565 . "insulin precursor [Canis lupus familiaris]" . . . . . 100.00 110 100.00 100.00 3.91e-05 . . . . 15464 1 281 no SP P01308 . "RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor" . . . . . 100.00 110 100.00 100.00 5.75e-05 . . . . 15464 1 282 no SP P01311 . "RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor" . . . . . 100.00 110 100.00 100.00 3.87e-05 . . . . 15464 1 283 no SP P01315 . "RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor" . . . . . 100.00 108 100.00 100.00 5.54e-05 . . . . 15464 1 284 no SP P01321 . "RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor" . . . . . 100.00 110 100.00 100.00 3.91e-05 . . . . 15464 1 285 no SP P30406 . "RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor" . . . . . 100.00 110 100.00 100.00 3.68e-05 . . . . 15464 1 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . GLY . 15464 1 2 . ILE . 15464 1 3 . VAL . 15464 1 4 . GLU . 15464 1 5 . GLN . 15464 1 6 . CYS . 15464 1 7 . CYS . 15464 1 8 . THR . 15464 1 9 . SER . 15464 1 10 . ILE . 15464 1 11 . CYS . 15464 1 12 . SER . 15464 1 13 . LEU . 15464 1 14 . TYR . 15464 1 15 . GLN . 15464 1 16 . LEU . 15464 1 17 . GLU . 15464 1 18 . ASN . 15464 1 19 . TYR . 15464 1 20 . CYS . 15464 1 21 . ASN . 15464 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . GLY 1 1 15464 1 . ILE 2 2 15464 1 . VAL 3 3 15464 1 . GLU 4 4 15464 1 . GLN 5 5 15464 1 . CYS 6 6 15464 1 . CYS 7 7 15464 1 . THR 8 8 15464 1 . SER 9 9 15464 1 . ILE 10 10 15464 1 . CYS 11 11 15464 1 . SER 12 12 15464 1 . LEU 13 13 15464 1 . TYR 14 14 15464 1 . GLN 15 15 15464 1 . LEU 16 16 15464 1 . GLU 17 17 15464 1 . ASN 18 18 15464 1 . TYR 19 19 15464 1 . CYS 20 20 15464 1 . ASN 21 21 15464 1 stop_ save_ save_entity_2 _Entity.Sf_category entity _Entity.Sf_framecode entity_2 _Entity.Entry_ID 15464 _Entity.ID 2 _Entity.BMRB_code . _Entity.Name 'chain B' _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID B _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; FVNQHLCGSHLVEALYLVCG ERGFFYTPKT ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 30 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'all disulfide bound' _Entity.Src_method man _Entity.Parent_entity_ID 2 _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight 3434.989 _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date 2015-01-30 loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID 1 no BMRB 1015 . "insulin B chain" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 2 no BMRB 1023 . "insulin B chain" . . . . . 73.33 42 100.00 100.00 4.32e-06 . . . . 15464 2 3 no BMRB 1025 . "insulin B chain" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 4 no BMRB 11016 . "Chain B" . . . . . 100.00 32 100.00 100.00 9.05e-13 . . . . 15464 2 5 no BMRB 1633 . "insulin B chain" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 6 no BMRB 16915 . "entity, chain 2" . . . . . 100.00 32 100.00 100.00 9.05e-13 . . . . 15464 2 7 no BMRB 17803 . "InsulinGR 2" . . . . . 100.00 31 100.00 100.00 9.98e-13 . . . . 15464 2 8 no BMRB 25260 . entity_2 . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 9 no BMRB 4266 . D-AlaB26_DTI-amide . . . . . 83.33 47 100.00 100.00 1.94e-08 . . . . 15464 2 10 no BMRB 555 . "insulin B chain" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 11 no BMRB 557 . "insulin B chain" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 12 no BMRB 937 . "insulin B chain" . . . . . 83.33 25 100.00 100.00 2.41e-08 . . . . 15464 2 13 no PDB 1AI0 . "R6 Human Insulin Hexamer (Non-Symmetric), Nmr, 10 Structures" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 14 no PDB 1AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 10 Structures" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 15 no PDB 1BEN . "Insulin Complexed With 4-Hydroxybenzamide" . . . . . 96.67 30 100.00 100.00 6.27e-12 . . . . 15464 2 16 no PDB 1BZV . "[d-Alab26]-Des(B27-B30)-Insulin-B26-Amide A Superpotent Single-Replacement Insulin Analogue, Nmr, Minimized Average Structure" . . . . . 83.33 26 100.00 100.00 2.41e-08 . . . . 15464 2 17 no PDB 1DEI . "Desheptapeptide (B24-B30) Insulin" . . . . . 76.67 23 100.00 100.00 8.22e-07 . . . . 15464 2 18 no PDB 1EFE . "An Active Mini-Proinsulin, M2pi" . . . . . 100.00 60 100.00 100.00 1.52e-12 . . . . 15464 2 19 no PDB 1EV3 . "Structure Of The Rhombohedral Form Of The M-cresol/insulin R6 Hexamer" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 20 no PDB 1EV6 . "Structure Of The Monoclinic Form Of The M-CresolINSULIN R6 Hexamer" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 21 no PDB 1EVR . "The Structure Of The ResorcinolINSULIN R6 HEXAMER" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 22 no PDB 1FU2 . "First Protein Structure Determined From X-Ray Powder Diffraction Data" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 23 no PDB 1FUB . "First Protein Structure Determined From X-Ray Powder Diffraction Data" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 24 no PDB 1G7A . "1.2 A Structure Of T3r3 Human Insulin At 100 K" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 25 no PDB 1G7B . "1.3 A Structure Of T3r3 Human Insulin At 100 K" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 26 no PDB 1GUJ . "Insulin At Ph 2: Structural Analysis Of The Conditions Promoting Insulin Fibre Formation." . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 27 no PDB 1HIS . "Structure And Dynamics Of Des-Pentapeptide-Insulin In Solution: The Molten-Globule Hypothesis" . . . . . 83.33 25 100.00 100.00 2.41e-08 . . . . 15464 2 28 no PDB 1HTV . "Crystal Structure Of Destripeptide (B28-B30) Insulin" . . . . . 90.00 27 100.00 100.00 5.25e-10 . . . . 15464 2 29 no PDB 1J73 . "Crystal Structure Of An Unstable Insulin Analog With Native Activity." . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 30 no PDB 1JCA . "Non-standard Design Of Unstable Insulin Analogues With Enhanced Activity" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 31 no PDB 1MSO . "T6 Human Insulin At 1.0 A Resolution" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 32 no PDB 1OS3 . "Dehydrated T6 Human Insulin At 100 K" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 33 no PDB 1OS4 . "Dehydrated T6 Human Insulin At 295 K" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 34 no PDB 1PID . "Bovine Despentapeptide Insulin" . . . . . 83.33 25 100.00 100.00 2.41e-08 . . . . 15464 2 35 no PDB 1Q4V . "Crystal Structure Of Allo-Ilea2-Insulin, An Inactive Chiral Analogue: Implications For The Mechanism Of Receptor" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 36 no PDB 1RWE . "Enhancing The Activity Of Insulin At Receptor Edge: Crystal Structure And Photo-Cross-Linking Of A8 Analogues" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 37 no PDB 1SDB . "Porcine Desb1-2 Despentapeptide(B26-B30) Insulin" . . . . . 76.67 23 100.00 100.00 5.38e-07 . . . . 15464 2 38 no PDB 1SF1 . "Nmr Structure Of Human Insulin Under Amyloidogenic Condition, 15 Structures" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 39 no PDB 1TRZ . "Crystallographic Evidence For Dual Coordination Around Zinc In The T3r3 Human Insulin Hexamer" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 40 no PDB 1TYL . "The Structure Of A Complex Of Hexameric Insulin And 4'- Hydroxyacetanilide" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 41 no PDB 1TYM . "The Structure Of A Complex Of Hexameric Insulin And 4'- Hydroxyacetanilide" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 42 no PDB 1UZ9 . "Crystallographic And Solution Studies Of N-Lithocholyl Insulin: A New Generation Of Prolonged-Acting Insulins." . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 43 no PDB 1XDA . "Structure Of Insulin" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 44 no PDB 1XGL . "Human Insulin Disulfide Isomer, Nmr, 10 Structures" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 45 no PDB 1XW7 . "Diabetes-Associated Mutations In Human Insulin: Crystal Structure And Photo-Cross-Linking Studies Of A-Chain Variant Insulin Wa" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 46 no PDB 1ZNJ . "Insulin, Monoclinic Crystal Form" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 47 no PDB 2AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 20 Structures" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 48 no PDB 2C8Q . "Insuline(1sec) And Uv Laser Excited Fluorescence" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 49 no PDB 2C8R . "Insuline(60sec) And Uv Laser Excited Fluorescence" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 50 no PDB 2CEU . "Despentapeptide Insulin In Acetic Acid (Ph 2)" . . . . . 83.33 25 100.00 100.00 2.41e-08 . . . . 15464 2 51 no PDB 2G54 . "Crystal Structure Of Zn-Bound Human Insulin-Degrading Enzyme In Complex With Insulin B Chain" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 52 no PDB 2G56 . "Crystal Structure Of Human Insulin-degrading Enzyme In Complex With Insulin B Chain" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 53 no PDB 2HIU . "Nmr Structure Of Human Insulin In 20% Acetic Acid, Zinc- Free, 10 Structures" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 54 no PDB 2JV1 . "Nmr Structure Of Human Insulin Monomer In 35% Cd3cn Zinc Free, 50 Structures" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 55 no PDB 2KXK . "Human Insulin Mutant A22gly-B31lys-B32arg" . . . . . 100.00 32 100.00 100.00 9.05e-13 . . . . 15464 2 56 no PDB 2LGB . "Modified A22gly-B31arg Human Insulin" . . . . . 100.00 31 100.00 100.00 9.98e-13 . . . . 15464 2 57 no PDB 2MVC . "Solution Structure Of Human Insulin At Ph 1.9" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 58 no PDB 2OLY . "Structure Of Human Insulin In Presence Of Urea At Ph 7.0" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 59 no PDB 2OLZ . "Structure Of Human Insulin In Presence Of Thiocyanate At Ph 7.0" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 60 no PDB 2OM0 . "Structure Of Human Insulin In Presence Of Urea At Ph 6.5" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 61 no PDB 2OM1 . "Structure Of Human Insulin In Presence Of Thiocyanate At Ph 6.5" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 62 no PDB 2OMG . "Structure Of Human Insulin Cocrystallized With Protamine And Urea" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 63 no PDB 2OMH . "Structure Of Human Insulin Cocrystallized With Arg-12 Peptide In Presence Of Urea" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 64 no PDB 2OMI . "Structure Of Human Insulin Cocrystallized With Protamine" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 65 no PDB 2QIU . "Structure Of Human Arg-Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 66 no PDB 2R34 . "Crystal Structure Of Mn Human Arg-Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 67 no PDB 2R35 . "Crystal Structure Of Rb Human Arg-Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 68 no PDB 2R36 . "Crystal Structure Of Ni Human Arg-Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 69 no PDB 2RN5 . "Humal Insulin Mutant B31lys-B32arg" . . . . . 100.00 32 100.00 100.00 9.05e-13 . . . . 15464 2 70 no PDB 2VJZ . "Crystal Structure Form Ultalente Insulin Microcrystals" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 71 no PDB 2VK0 . "Crystal Structure Form Ultalente Insulin Microcrystals" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 72 no PDB 2W44 . "Structure Deltaa1-a4 Insulin" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 73 no PDB 2WBY . "Crystal Structure Of Human Insulin-Degrading Enzyme In Complex With Insulin" . . . . . 63.33 19 100.00 100.00 1.44e-03 . . . . 15464 2 74 no PDB 2WC0 . "Crystal Structure Of Human Insulin Degrading Enzyme In Complex With Iodinated Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 75 no PDB 2WRU . "Semi-synthetic Highly Active Analogue Of Human Insulin Nmealab26-dti-nh2" . . . . . 83.33 26 100.00 100.00 2.41e-08 . . . . 15464 2 76 no PDB 2WRV . "Semi-Synthetic Highly Active Analogue Of Human Insulin Nmehisb26-Dti-Nh2" . . . . . 83.33 26 100.00 100.00 2.41e-08 . . . . 15464 2 77 no PDB 2WRW . "Semi-Synthetic Highly Active Analogue Of Human Insulin D- Prob26-Dti-Nh2" . . . . . 83.33 26 100.00 100.00 2.41e-08 . . . . 15464 2 78 no PDB 2WS4 . "Semi-Synthetic Analogue Of Human Insulin Prob26-Dti In Monomer Form" . . . . . 83.33 26 100.00 100.00 2.57e-08 . . . . 15464 2 79 no PDB 2WS6 . "Semi-Synthetic Analogue Of Human Insulin Nmetyrb26-Insulin In Hexamer Form" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 80 no PDB 2WS7 . "Semi-Synthetic Analogue Of Human Insulin Prob26-Dti" . . . . . 83.33 26 100.00 100.00 2.57e-08 . . . . 15464 2 81 no PDB 3AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, Refined Average Structure" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 82 no PDB 3E7Y . "Structure Of Human Insulin" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 83 no PDB 3E7Z . "Structure Of Human Insulin" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 84 no PDB 3EXX . "Structure Of The T6 Human Insulin Derivative With Nickel At 1.35 A Resolution" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 85 no PDB 3FQ9 . "Design Of An Insulin Analog With Enhanced Receptor-Binding Selectivity. Rationale, Structure, And Therapeutic Implications" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 86 no PDB 3ILG . "Crystal Structure Of Humnan Insulin Sr+2 Complex" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 87 no PDB 3INC . "Crystal Structure Of Human Insulin With Ni+2 Complex" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 88 no PDB 3IR0 . "Crystal Structure Of Human Insulin Complexed With Cu+2 Metal Ion" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 89 no PDB 3KQ6 . "Enhancing The Therapeutic Properties Of A Protein By A Desig Binding Site, Structural Principles Of A Novel Long-Acting Analog" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 90 no PDB 3P33 . "Insulin Fibrillation Is The Janus Face Of Induced Fit. A Chiral Clamp Stabilizes The Native State At The Expense Of Activity" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 91 no PDB 3Q6E . "Human Insulin In Complex With Cucurbit[7]uril" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 92 no PDB 3TT8 . "Crystal Structure Analysis Of Cu Human Insulin Derivative" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 93 no PDB 3V19 . "Forestalling Insulin Fibrillation By Insertion Of A Chiral Clamp Mechanism-Based Application Of Protein Engineering To Global H" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 94 no PDB 3W11 . "Insulin Receptor Ectodomain Construct Comprising Domains L1-cr In Complex With Human Insulin, Alpha-ct Peptide(704-719) And Fab" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 95 no PDB 3W12 . "Insulin Receptor Ectodomain Construct Comprising Domains L1-cr In Complex With High-affinity Insulin Analogue [d-pro-b26]-dti-n" . . . . . 83.33 26 100.00 100.00 2.41e-08 . . . . 15464 2 96 no PDB 3W13 . "Insulin Receptor Ectodomain Construct Comprising Domains L1-cr In Complex With High-affinity Insulin Analogue [d-pro-b26]-dti-n" . . . . . 83.33 26 100.00 100.00 2.41e-08 . . . . 15464 2 97 no PDB 3W7Y . "0.92a Structure Of 2zn Human Insulin At 100k" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 98 no PDB 3W7Z . "1.15a Structure Of Human 2zn Insulin At 293k" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 99 no PDB 3W80 . "Crystal Structure Of Dodecamer Human Insulin With Double C-axis Length Of The Hexamer 2 Zn Insulin Cell" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 100 no PDB 3ZU1 . "Structure Of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 101 no PDB 4AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 'green' Substate, Average Structure" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 102 no PDB 4AJX . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 103 no PDB 4AJZ . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 104 no PDB 4AK0 . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 105 no PDB 4AKJ . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 106 no PDB 4EWW . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 107 no PDB 4EWX . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 108 no PDB 4EWZ . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 109 no PDB 4EX0 . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 110 no PDB 4EX1 . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 111 no PDB 4EXX . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 112 no PDB 4EY1 . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 113 no PDB 4EY9 . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 114 no PDB 4EYD . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 115 no PDB 4EYN . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 116 no PDB 4EYP . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 117 no PDB 4F0N . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 118 no PDB 4F0O . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 119 no PDB 4F1A . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 120 no PDB 4F1B . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 121 no PDB 4F1C . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 122 no PDB 4F1D . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 123 no PDB 4F1F . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 124 no PDB 4F1G . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 125 no PDB 4F4T . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 126 no PDB 4F4V . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 127 no PDB 4F51 . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 128 no PDB 4F8F . "Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 129 no PDB 4FG3 . "Crystal Structure Analysis Of The Human Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 130 no PDB 4FKA . "High Resolution Structure Of The Manganese Derivative Of Insulin" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 131 no PDB 4IYD . "Insulin Glargine Crystal Structure 1" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 132 no PDB 4IYF . "Insulin Glargine Crystal Structure 2" . . . . . 96.67 29 100.00 100.00 5.84e-12 . . . . 15464 2 133 no PDB 4OGA . "Insulin In Complex With Site 1 Of The Human Insulin Receptor" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 134 no PDB 5AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 'red' Substate, Average Structure" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 135 no PDB 6INS . "X-Ray Analysis Of The Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue" . . . . . 96.67 50 100.00 100.00 5.96e-12 . . . . 15464 2 136 no DBJ BAH59081 . "human M-proinsulin [synthetic construct]" . . . . . 100.00 87 100.00 100.00 1.24e-12 . . . . 15464 2 137 no DBJ BAJ17943 . "insulin [synthetic construct]" . . . . . 100.00 110 100.00 100.00 1.27e-12 . . . . 15464 2 138 no EMBL CAA08766 . "insulin [Homo sapiens]" . . . . . 100.00 59 100.00 100.00 2.70e-13 . . . . 15464 2 139 no EMBL CAA23424 . "unnamed protein product [synthetic construct]" . . . . . 100.00 87 100.00 100.00 1.24e-12 . . . . 15464 2 140 no EMBL CAA23828 . "preproinsulin [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 1.27e-12 . . . . 15464 2 141 no EMBL CAA43403 . "Preproinsulin [Pan troglodytes]" . . . . . 100.00 110 100.00 100.00 1.28e-12 . . . . 15464 2 142 no EMBL CAA43405 . "Preproinsulin [Chlorocebus aethiops]" . . . . . 100.00 110 100.00 100.00 1.42e-12 . . . . 15464 2 143 no GB AAA36849 . "preproinsulin [Macaca fascicularis]" . . . . . 100.00 110 100.00 100.00 1.32e-12 . . . . 15464 2 144 no GB AAA59172 . "insulin [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 1.27e-12 . . . . 15464 2 145 no GB AAA59173 . "insulin [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 1.27e-12 . . . . 15464 2 146 no GB AAA59179 . "insulin [Homo sapiens]" . . . . . 100.00 107 100.00 100.00 1.19e-12 . . . . 15464 2 147 no GB AAA72171 . "insulin B chain [synthetic construct]" . . . . . 100.00 31 100.00 100.00 8.78e-13 . . . . 15464 2 148 no PIR INEL . "insulin - elephant" . . . . . 100.00 51 100.00 100.00 1.54e-12 . . . . 15464 2 149 no PRF 0510475A . "insulin B,24/25-Leu" . . . . . 100.00 30 100.00 100.00 1.09e-12 . . . . 15464 2 150 no PRF 0601246A . insulin,prepro . . . . . 100.00 110 100.00 100.00 1.27e-12 . . . . 15464 2 151 no PRF 1006230A . insulin,pro- . . . . . 100.00 86 100.00 100.00 1.46e-12 . . . . 15464 2 152 no PRF 600165A . insulin . . . . . 100.00 51 100.00 100.00 1.19e-12 . . . . 15464 2 153 no PRF 640291A . insulin . . . . . 93.33 51 100.00 100.00 3.62e-11 . . . . 15464 2 154 no REF NP_000198 . "insulin preproprotein [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 1.27e-12 . . . . 15464 2 155 no REF NP_001008996 . "insulin preproprotein [Pan troglodytes]" . . . . . 100.00 110 100.00 100.00 1.28e-12 . . . . 15464 2 156 no REF NP_001035835 . "insulin, isoform 2 precursor [Homo sapiens]" . . . . . 100.00 200 100.00 100.00 3.17e-14 . . . . 15464 2 157 no REF NP_001172026 . "insulin preproprotein [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 1.27e-12 . . . . 15464 2 158 no REF NP_001172027 . "insulin preproprotein [Homo sapiens]" . . . . . 100.00 110 100.00 100.00 1.27e-12 . . . . 15464 2 159 no SP F8WCM5 . "RecName: Full=Insulin, isoform 2; AltName: Full=INS-IGF2 readthrough transcript protein [Homo sapiens]" . . . . . 100.00 200 100.00 100.00 3.17e-14 . . . . 15464 2 160 no SP P01308 . "RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor [Homo" . . . . . 100.00 110 100.00 100.00 1.27e-12 . . . . 15464 2 161 no SP P01316 . "RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain, partial [Elephas maxim" . . . . . 100.00 51 100.00 100.00 1.54e-12 . . . . 15464 2 162 no SP P30406 . "RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor [Maca" . . . . . 100.00 110 100.00 100.00 1.32e-12 . . . . 15464 2 163 no SP P30407 . "RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor [Chlo" . . . . . 100.00 110 100.00 100.00 1.42e-12 . . . . 15464 2 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . PHE . 15464 2 2 . VAL . 15464 2 3 . ASN . 15464 2 4 . GLN . 15464 2 5 . HIS . 15464 2 6 . LEU . 15464 2 7 . CYS . 15464 2 8 . GLY . 15464 2 9 . SER . 15464 2 10 . HIS . 15464 2 11 . LEU . 15464 2 12 . VAL . 15464 2 13 . GLU . 15464 2 14 . ALA . 15464 2 15 . LEU . 15464 2 16 . TYR . 15464 2 17 . LEU . 15464 2 18 . VAL . 15464 2 19 . CYS . 15464 2 20 . GLY . 15464 2 21 . GLU . 15464 2 22 . ARG . 15464 2 23 . GLY . 15464 2 24 . PHE . 15464 2 25 . PHE . 15464 2 26 . TYR . 15464 2 27 . THR . 15464 2 28 . PRO . 15464 2 29 . LYS . 15464 2 30 . THR . 15464 2 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . PHE 1 1 15464 2 . VAL 2 2 15464 2 . ASN 3 3 15464 2 . GLN 4 4 15464 2 . HIS 5 5 15464 2 . LEU 6 6 15464 2 . CYS 7 7 15464 2 . GLY 8 8 15464 2 . SER 9 9 15464 2 . HIS 10 10 15464 2 . LEU 11 11 15464 2 . VAL 12 12 15464 2 . GLU 13 13 15464 2 . ALA 14 14 15464 2 . LEU 15 15 15464 2 . TYR 16 16 15464 2 . LEU 17 17 15464 2 . VAL 18 18 15464 2 . CYS 19 19 15464 2 . GLY 20 20 15464 2 . GLU 21 21 15464 2 . ARG 22 22 15464 2 . GLY 23 23 15464 2 . PHE 24 24 15464 2 . PHE 25 25 15464 2 . TYR 26 26 15464 2 . THR 27 27 15464 2 . PRO 28 28 15464 2 . LYS 29 29 15464 2 . THR 30 30 15464 2 stop_ save_ #################### # Natural source # #################### save_natural_source _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source _Entity_natural_src_list.Entry_ID 15464 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Subvariant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Cellular_location _Entity_natural_src.Fragment _Entity_natural_src.Fraction _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Plasmid_details _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Dev_stage _Entity_natural_src.Details _Entity_natural_src.Citation_ID _Entity_natural_src.Citation_label _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $entity_1 . 9606 organism . 'Homo sapiens' Human . . Eukaryota Metazoa Homo sapiens . . . . . . . . . . . . . . . . . . . . . 15464 1 2 2 $entity_2 . 9606 organism . 'Homo sapiens' Human . . Eukaryota Metazoa Homo sapiens . . . . . . . . . . . . . . . . . . . . . 15464 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source _Entity_experimental_src_list.Entry_ID 15464 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_subvariant _Entity_experimental_src.Host_org_organ _Entity_experimental_src.Host_org_tissue _Entity_experimental_src.Host_org_tissue_fraction _Entity_experimental_src.Host_org_cell_line _Entity_experimental_src.Host_org_cell_type _Entity_experimental_src.Host_org_cellular_location _Entity_experimental_src.Host_org_organelle _Entity_experimental_src.Host_org_gene _Entity_experimental_src.Host_org_culture_collection _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Host_org_dev_stage _Entity_experimental_src.Details _Entity_experimental_src.Citation_ID _Entity_experimental_src.Citation_label _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 1 $entity_1 . 'obtained from a vendor' . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15464 1 2 2 $entity_2 . 'obtained from a vendor' . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15464 1 stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_1 _Sample.Sf_category sample _Sample.Sf_framecode sample_1 _Sample.Entry_ID 15464 _Sample.ID 1 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system '35% CD3CN/ 65%H2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 entity_1 'natural abundance' . . 1 $entity_1 . . 2.0 . . mM . . . . 15464 1 2 entity_2 'natural abundance' . . 2 $entity_2 . . 2.0 . . mM . . . . 15464 1 3 CD3CN 'natural abundance' . . . . . . 35 . . % . . . . 15464 1 4 H2O 'natural abundance' . . . . . . 65 . . % . . . . 15464 1 stop_ save_ ####################### # Sample conditions # ####################### save_sample_conditions_1 _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_conditions_1 _Sample_condition_list.Entry_ID 15464 _Sample_condition_list.ID 1 _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH 3.6 . pH 15464 1 pressure 1 . atm 15464 1 temperature 303 . K 15464 1 stop_ save_ ############################ # Computer software used # ############################ save_AMBER _Software.Sf_category software _Software.Sf_framecode AMBER _Software.Entry_ID 15464 _Software.ID 1 _Software.Name AMBER _Software.Version 9 _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, ... and Koll' . . 15464 1 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID refinement 15464 1 'structure solution' 15464 1 stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_1 _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode spectrometer_1 _NMR_spectrometer.Entry_ID 15464 _NMR_spectrometer.ID 1 _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Varian _NMR_spectrometer.Model 'Uniform NMR System' _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 500 save_ save_NMR_spectrometer_list _NMR_spectrometer_list.Sf_category NMR_spectrometer_list _NMR_spectrometer_list.Sf_framecode NMR_spectrometer_list _NMR_spectrometer_list.Entry_ID 15464 _NMR_spectrometer_list.ID 1 loop_ _NMR_spectrometer_view.ID _NMR_spectrometer_view.Name _NMR_spectrometer_view.Manufacturer _NMR_spectrometer_view.Model _NMR_spectrometer_view.Serial_number _NMR_spectrometer_view.Field_strength _NMR_spectrometer_view.Details _NMR_spectrometer_view.Citation_ID _NMR_spectrometer_view.Citation_label _NMR_spectrometer_view.Entry_ID _NMR_spectrometer_view.NMR_spectrometer_list_ID 1 spectrometer_1 Varian 'Uniform NMR System' . 500 . . . 15464 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_experiment_list _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list _Experiment_list.Entry_ID 15464 _Experiment_list.ID 1 _Experiment_list.Details . loop_ _Experiment.ID _Experiment.Name _Experiment.Raw_data_flag _Experiment.NMR_spec_expt_ID _Experiment.NMR_spec_expt_label _Experiment.MS_expt_ID _Experiment.MS_expt_label _Experiment.SAXS_expt_ID _Experiment.SAXS_expt_label _Experiment.FRET_expt_ID _Experiment.FRET_expt_label _Experiment.EMR_expt_ID _Experiment.EMR_expt_label _Experiment.Sample_ID _Experiment.Sample_label _Experiment.Sample_state _Experiment.Sample_volume _Experiment.Sample_volume_units _Experiment.Sample_condition_list_ID _Experiment.Sample_condition_list_label _Experiment.Sample_spinning_rate _Experiment.Sample_angle _Experiment.NMR_tube_type _Experiment.NMR_spectrometer_ID _Experiment.NMR_spectrometer_label _Experiment.NMR_spectrometer_probe_ID _Experiment.NMR_spectrometer_probe_label _Experiment.NMR_spectral_processing_ID _Experiment.NMR_spectral_processing_label _Experiment.Mass_spectrometer_ID _Experiment.Mass_spectrometer_label _Experiment.Xray_instrument_ID _Experiment.Xray_instrument_label _Experiment.Fluorescence_instrument_ID _Experiment.Fluorescence_instrument_label _Experiment.EMR_instrument_ID _Experiment.EMR_instrument_label _Experiment.Chromatographic_system_ID _Experiment.Chromatographic_system_label _Experiment.Chromatographic_column_ID _Experiment.Chromatographic_column_label _Experiment.Entry_ID _Experiment.Experiment_list_ID 1 '2D 1H-1H NOESY' no . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 15464 1 2 '2D 1H-1H TOCSY' no . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . 1 $spectrometer_1 . . . . . . . . . . . . . . . . 15464 1 stop_ save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chemical_shift_reference_1 _Chem_shift_reference.Sf_category chem_shift_reference _Chem_shift_reference.Sf_framecode chemical_shift_reference_1 _Chem_shift_reference.Entry_ID 15464 _Chem_shift_reference.ID 1 _Chem_shift_reference.Details . loop_ _Chem_shift_ref.Atom_type _Chem_shift_ref.Atom_isotope_number _Chem_shift_ref.Mol_common_name _Chem_shift_ref.Atom_group _Chem_shift_ref.Concentration_val _Chem_shift_ref.Concentration_units _Chem_shift_ref.Solvent _Chem_shift_ref.Rank _Chem_shift_ref.Chem_shift_units _Chem_shift_ref.Chem_shift_val _Chem_shift_ref.Ref_method _Chem_shift_ref.Ref_type _Chem_shift_ref.Indirect_shift_ratio _Chem_shift_ref.External_ref_loc _Chem_shift_ref.External_ref_sample_geometry _Chem_shift_ref.External_ref_axis _Chem_shift_ref.Indirect_shift_ratio_cit_ID _Chem_shift_ref.Indirect_shift_ratio_cit_label _Chem_shift_ref.Ref_correction_type _Chem_shift_ref.Correction_val _Chem_shift_ref.Correction_val_cit_ID _Chem_shift_ref.Correction_val_cit_label _Chem_shift_ref.Entry_ID _Chem_shift_ref.Chem_shift_reference_ID H 1 DSS 'methyl protons' . . . . ppm 0.00 internal direct 1.000000000 . . . 1 $entry_citation . . 1 $entry_citation 15464 1 stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_assigned_chem_shift_list_1 _Assigned_chem_shift_list.Sf_category assigned_chemical_shifts _Assigned_chem_shift_list.Sf_framecode assigned_chem_shift_list_1 _Assigned_chem_shift_list.Entry_ID 15464 _Assigned_chem_shift_list.ID 1 _Assigned_chem_shift_list.Sample_condition_list_ID 1 _Assigned_chem_shift_list.Sample_condition_list_label $sample_conditions_1 _Assigned_chem_shift_list.Chem_shift_reference_ID 1 _Assigned_chem_shift_list.Chem_shift_reference_label $chemical_shift_reference_1 _Assigned_chem_shift_list.Chem_shift_1H_err . _Assigned_chem_shift_list.Chem_shift_13C_err . _Assigned_chem_shift_list.Chem_shift_15N_err . _Assigned_chem_shift_list.Chem_shift_31P_err . _Assigned_chem_shift_list.Chem_shift_2H_err . _Assigned_chem_shift_list.Chem_shift_19F_err . _Assigned_chem_shift_list.Error_derivation_method . _Assigned_chem_shift_list.Details . _Assigned_chem_shift_list.Text_data_format . _Assigned_chem_shift_list.Text_data . loop_ _Chem_shift_experiment.Experiment_ID _Chem_shift_experiment.Experiment_name _Chem_shift_experiment.Sample_ID _Chem_shift_experiment.Sample_label _Chem_shift_experiment.Sample_state _Chem_shift_experiment.Entry_ID _Chem_shift_experiment.Assigned_chem_shift_list_ID 1 '2D 1H-1H NOESY' . . . 15464 1 stop_ loop_ _Atom_chem_shift.ID _Atom_chem_shift.Assembly_atom_ID _Atom_chem_shift.Entity_assembly_ID _Atom_chem_shift.Entity_ID _Atom_chem_shift.Comp_index_ID _Atom_chem_shift.Seq_ID _Atom_chem_shift.Comp_ID _Atom_chem_shift.Atom_ID _Atom_chem_shift.Atom_type _Atom_chem_shift.Atom_isotope_number _Atom_chem_shift.Val _Atom_chem_shift.Val_err _Atom_chem_shift.Assign_fig_of_merit _Atom_chem_shift.Ambiguity_code _Atom_chem_shift.Occupancy _Atom_chem_shift.Resonance_ID _Atom_chem_shift.Auth_entity_assembly_ID _Atom_chem_shift.Auth_asym_ID _Atom_chem_shift.Auth_seq_ID _Atom_chem_shift.Auth_comp_ID _Atom_chem_shift.Auth_atom_ID _Atom_chem_shift.Details _Atom_chem_shift.Entry_ID _Atom_chem_shift.Assigned_chem_shift_list_ID 1 . 1 1 1 1 GLY HA2 H 1 3.954 0.02 . 1 . . . . 1 GLY HA2 . 15464 1 2 . 1 1 1 1 GLY HA3 H 1 3.954 0.02 . 1 . . . . 1 GLY HA3 . 15464 1 3 . 1 1 2 2 ILE H H 1 8.422 0.02 . 1 . . . . 2 ILE H . 15464 1 4 . 1 1 2 2 ILE HA H 1 3.887 0.02 . 1 . . . . 2 ILE HA . 15464 1 5 . 1 1 2 2 ILE HB H 1 1.261 0.02 . 1 . . . . 2 ILE HB . 15464 1 6 . 1 1 2 2 ILE HD11 H 1 0.638 0.02 . 1 . . . . 2 ILE HD1 . 15464 1 7 . 1 1 2 2 ILE HD12 H 1 0.638 0.02 . 1 . . . . 2 ILE HD1 . 15464 1 8 . 1 1 2 2 ILE HD13 H 1 0.638 0.02 . 1 . . . . 2 ILE HD1 . 15464 1 9 . 1 1 2 2 ILE HG12 H 1 1.170 0.02 . 2 . . . . 2 ILE HG12 . 15464 1 10 . 1 1 2 2 ILE HG21 H 1 0.750 0.02 . 1 . . . . 2 ILE HG2 . 15464 1 11 . 1 1 2 2 ILE HG22 H 1 0.750 0.02 . 1 . . . . 2 ILE HG2 . 15464 1 12 . 1 1 2 2 ILE HG23 H 1 0.750 0.02 . 1 . . . . 2 ILE HG2 . 15464 1 13 . 1 1 3 3 VAL H H 1 8.081 0.02 . 1 . . . . 3 VAL H . 15464 1 14 . 1 1 3 3 VAL HA H 1 3.624 0.02 . 1 . . . . 3 VAL HA . 15464 1 15 . 1 1 3 3 VAL HB H 1 1.929 0.02 . 1 . . . . 3 VAL HB . 15464 1 16 . 1 1 3 3 VAL HG11 H 1 0.922 0.02 . 2 . . . . 3 VAL HG1 . 15464 1 17 . 1 1 3 3 VAL HG12 H 1 0.922 0.02 . 2 . . . . 3 VAL HG1 . 15464 1 18 . 1 1 3 3 VAL HG13 H 1 0.922 0.02 . 2 . . . . 3 VAL HG1 . 15464 1 19 . 1 1 3 3 VAL HG21 H 1 0.876 0.02 . 2 . . . . 3 VAL HG2 . 15464 1 20 . 1 1 3 3 VAL HG22 H 1 0.876 0.02 . 2 . . . . 3 VAL HG2 . 15464 1 21 . 1 1 3 3 VAL HG23 H 1 0.876 0.02 . 2 . . . . 3 VAL HG2 . 15464 1 22 . 1 1 4 4 GLU H H 1 8.147 0.02 . 1 . . . . 4 GLU H . 15464 1 23 . 1 1 4 4 GLU HA H 1 4.164 0.02 . 1 . . . . 4 GLU HA . 15464 1 24 . 1 1 4 4 GLU HB2 H 1 2.072 0.02 . 2 . . . . 4 GLU HB2 . 15464 1 25 . 1 1 4 4 GLU HB3 H 1 2.020 0.02 . 2 . . . . 4 GLU HB3 . 15464 1 26 . 1 1 4 4 GLU HG2 H 1 2.481 0.02 . 2 . . . . 4 GLU HG2 . 15464 1 27 . 1 1 4 4 GLU HG3 H 1 2.378 0.02 . 2 . . . . 4 GLU HG3 . 15464 1 28 . 1 1 5 5 GLN H H 1 8.193 0.02 . 1 . . . . 5 GLN H . 15464 1 29 . 1 1 5 5 GLN HA H 1 4.040 0.02 . 1 . . . . 5 GLN HA . 15464 1 30 . 1 1 5 5 GLN HB2 H 1 2.084 0.02 . 2 . . . . 5 GLN HB2 . 15464 1 31 . 1 1 5 5 GLN HB3 H 1 2.025 0.02 . 2 . . . . 5 GLN HB3 . 15464 1 32 . 1 1 5 5 GLN HE21 H 1 6.751 0.02 . 2 . . . . 5 GLN HE21 . 15464 1 33 . 1 1 5 5 GLN HE22 H 1 7.441 0.02 . 2 . . . . 5 GLN HE22 . 15464 1 34 . 1 1 5 5 GLN HG2 H 1 2.426 0.02 . 2 . . . . 5 GLN HG2 . 15464 1 35 . 1 1 5 5 GLN HG3 H 1 2.361 0.02 . 2 . . . . 5 GLN HG3 . 15464 1 36 . 1 1 6 6 CYS H H 1 8.172 0.02 . 1 . . . . 6 CYS H . 15464 1 37 . 1 1 6 6 CYS HA H 1 4.844 0.02 . 1 . . . . 6 CYS HA . 15464 1 38 . 1 1 6 6 CYS HB2 H 1 2.867 0.02 . 1 . . . . 6 CYS HB2 . 15464 1 39 . 1 1 6 6 CYS HB3 H 1 3.249 0.02 . 1 . . . . 6 CYS HB3 . 15464 1 40 . 1 1 7 7 CYS H H 1 8.245 0.02 . 1 . . . . 7 CYS H . 15464 1 41 . 1 1 7 7 CYS HA H 1 4.798 0.02 . 1 . . . . 7 CYS HA . 15464 1 42 . 1 1 7 7 CYS HB2 H 1 3.689 0.02 . 1 . . . . 7 CYS HB2 . 15464 1 43 . 1 1 7 7 CYS HB3 H 1 3.307 0.02 . 1 . . . . 7 CYS HB3 . 15464 1 44 . 1 1 8 8 THR H H 1 8.072 0.02 . 1 . . . . 8 THR H . 15464 1 45 . 1 1 8 8 THR HA H 1 4.062 0.02 . 1 . . . . 8 THR HA . 15464 1 46 . 1 1 8 8 THR HB H 1 4.371 0.02 . 1 . . . . 8 THR HB . 15464 1 47 . 1 1 8 8 THR HG21 H 1 1.211 0.02 . 1 . . . . 8 THR HG2 . 15464 1 48 . 1 1 8 8 THR HG22 H 1 1.211 0.02 . 1 . . . . 8 THR HG2 . 15464 1 49 . 1 1 8 8 THR HG23 H 1 1.211 0.02 . 1 . . . . 8 THR HG2 . 15464 1 50 . 1 1 9 9 SER H H 1 7.333 0.02 . 1 . . . . 9 SER H . 15464 1 51 . 1 1 9 9 SER HA H 1 4.682 0.02 . 1 . . . . 9 SER HA . 15464 1 52 . 1 1 9 9 SER HB2 H 1 3.993 0.02 . 2 . . . . 9 SER HB2 . 15464 1 53 . 1 1 9 9 SER HB3 H 1 3.840 0.02 . 2 . . . . 9 SER HB3 . 15464 1 54 . 1 1 10 10 ILE H H 1 7.747 0.02 . 1 . . . . 10 ILE H . 15464 1 55 . 1 1 10 10 ILE HA H 1 4.423 0.02 . 1 . . . . 10 ILE HA . 15464 1 56 . 1 1 10 10 ILE HB H 1 1.563 0.02 . 1 . . . . 10 ILE HB . 15464 1 57 . 1 1 10 10 ILE HD11 H 1 0.588 0.02 . 1 . . . . 10 ILE HD1 . 15464 1 58 . 1 1 10 10 ILE HD12 H 1 0.588 0.02 . 1 . . . . 10 ILE HD1 . 15464 1 59 . 1 1 10 10 ILE HD13 H 1 0.588 0.02 . 1 . . . . 10 ILE HD1 . 15464 1 60 . 1 1 10 10 ILE HG12 H 1 1.168 0.02 . 2 . . . . 10 ILE HG12 . 15464 1 61 . 1 1 10 10 ILE HG13 H 1 0.588 0.02 . 2 . . . . 10 ILE HG13 . 15464 1 62 . 1 1 10 10 ILE HG21 H 1 0.671 0.02 . 1 . . . . 10 ILE HG2 . 15464 1 63 . 1 1 10 10 ILE HG22 H 1 0.671 0.02 . 1 . . . . 10 ILE HG2 . 15464 1 64 . 1 1 10 10 ILE HG23 H 1 0.671 0.02 . 1 . . . . 10 ILE HG2 . 15464 1 65 . 1 1 11 11 CYS H H 1 9.358 0.02 . 1 . . . . 11 CYS H . 15464 1 66 . 1 1 11 11 CYS HA H 1 5.025 0.02 . 1 . . . . 11 CYS HA . 15464 1 67 . 1 1 11 11 CYS HB2 H 1 3.278 0.02 . 2 . . . . 11 CYS HB2 . 15464 1 68 . 1 1 11 11 CYS HB3 H 1 3.068 0.02 . 2 . . . . 11 CYS HB3 . 15464 1 69 . 1 1 12 12 SER H H 1 8.543 0.02 . 1 . . . . 12 SER H . 15464 1 70 . 1 1 12 12 SER HA H 1 4.579 0.02 . 1 . . . . 12 SER HA . 15464 1 71 . 1 1 12 12 SER HB2 H 1 4.262 0.02 . 1 . . . . 12 SER HB2 . 15464 1 72 . 1 1 12 12 SER HB3 H 1 3.944 0.02 . 1 . . . . 12 SER HB3 . 15464 1 73 . 1 1 13 13 LEU H H 1 8.574 0.02 . 1 . . . . 13 LEU H . 15464 1 74 . 1 1 13 13 LEU HA H 1 3.951 0.02 . 1 . . . . 13 LEU HA . 15464 1 75 . 1 1 13 13 LEU HB2 H 1 1.525 0.02 . 2 . . . . 13 LEU HB2 . 15464 1 76 . 1 1 13 13 LEU HB3 H 1 1.426 0.02 . 2 . . . . 13 LEU HB3 . 15464 1 77 . 1 1 13 13 LEU HD11 H 1 0.872 0.02 . 1 . . . . 13 LEU HD1 . 15464 1 78 . 1 1 13 13 LEU HD12 H 1 0.872 0.02 . 1 . . . . 13 LEU HD1 . 15464 1 79 . 1 1 13 13 LEU HD13 H 1 0.872 0.02 . 1 . . . . 13 LEU HD1 . 15464 1 80 . 1 1 13 13 LEU HD21 H 1 0.799 0.02 . 1 . . . . 13 LEU HD2 . 15464 1 81 . 1 1 13 13 LEU HD22 H 1 0.799 0.02 . 1 . . . . 13 LEU HD2 . 15464 1 82 . 1 1 13 13 LEU HD23 H 1 0.799 0.02 . 1 . . . . 13 LEU HD2 . 15464 1 83 . 1 1 13 13 LEU HG H 1 1.530 0.02 . 1 . . . . 13 LEU HG . 15464 1 84 . 1 1 14 14 TYR H H 1 7.432 0.02 . 1 . . . . 14 TYR H . 15464 1 85 . 1 1 14 14 TYR HA H 1 4.144 0.02 . 1 . . . . 14 TYR HA . 15464 1 86 . 1 1 14 14 TYR HB2 H 1 2.975 0.02 . 2 . . . . 14 TYR HB2 . 15464 1 87 . 1 1 14 14 TYR HB3 H 1 2.904 0.02 . 2 . . . . 14 TYR HB3 . 15464 1 88 . 1 1 14 14 TYR HD1 H 1 7.068 0.02 . 3 . . . . 14 TYR HD1 . 15464 1 89 . 1 1 14 14 TYR HE1 H 1 6.827 0.02 . 3 . . . . 14 TYR HE1 . 15464 1 90 . 1 1 15 15 GLN H H 1 7.506 0.02 . 1 . . . . 15 GLN H . 15464 1 91 . 1 1 15 15 GLN HA H 1 3.974 0.02 . 1 . . . . 15 GLN HA . 15464 1 92 . 1 1 15 15 GLN HB2 H 1 2.347 0.02 . 2 . . . . 15 GLN HB2 . 15464 1 93 . 1 1 15 15 GLN HB3 H 1 2.005 0.02 . 2 . . . . 15 GLN HB3 . 15464 1 94 . 1 1 15 15 GLN HE21 H 1 6.856 0.02 . 2 . . . . 15 GLN HE21 . 15464 1 95 . 1 1 15 15 GLN HE22 H 1 7.382 0.02 . 2 . . . . 15 GLN HE22 . 15464 1 96 . 1 1 15 15 GLN HG2 H 1 2.419 0.02 . 2 . . . . 15 GLN HG2 . 15464 1 97 . 1 1 15 15 GLN HG3 H 1 2.351 0.02 . 2 . . . . 15 GLN HG3 . 15464 1 98 . 1 1 16 16 LEU H H 1 7.966 0.02 . 1 . . . . 16 LEU H . 15464 1 99 . 1 1 16 16 LEU HA H 1 4.133 0.02 . 1 . . . . 16 LEU HA . 15464 1 100 . 1 1 16 16 LEU HB2 H 1 1.879 0.02 . 2 . . . . 16 LEU HB2 . 15464 1 101 . 1 1 16 16 LEU HB3 H 1 1.591 0.02 . 2 . . . . 16 LEU HB3 . 15464 1 102 . 1 1 16 16 LEU HD11 H 1 0.811 0.02 . 1 . . . . 16 LEU HD1 . 15464 1 103 . 1 1 16 16 LEU HD12 H 1 0.811 0.02 . 1 . . . . 16 LEU HD1 . 15464 1 104 . 1 1 16 16 LEU HD13 H 1 0.811 0.02 . 1 . . . . 16 LEU HD1 . 15464 1 105 . 1 1 16 16 LEU HD21 H 1 0.772 0.02 . 1 . . . . 16 LEU HD2 . 15464 1 106 . 1 1 16 16 LEU HD22 H 1 0.772 0.02 . 1 . . . . 16 LEU HD2 . 15464 1 107 . 1 1 16 16 LEU HD23 H 1 0.772 0.02 . 1 . . . . 16 LEU HD2 . 15464 1 108 . 1 1 16 16 LEU HG H 1 1.722 0.02 . 1 . . . . 16 LEU HG . 15464 1 109 . 1 1 17 17 GLU H H 1 7.985 0.02 . 1 . . . . 17 GLU H . 15464 1 110 . 1 1 17 17 GLU HA H 1 4.143 0.02 . 1 . . . . 17 GLU HA . 15464 1 111 . 1 1 17 17 GLU HB2 H 1 2.075 0.02 . 2 . . . . 17 GLU HB2 . 15464 1 112 . 1 1 17 17 GLU HB3 H 1 2.017 0.02 . 2 . . . . 17 GLU HB3 . 15464 1 113 . 1 1 17 17 GLU HG2 H 1 2.544 0.02 . 2 . . . . 17 GLU HG2 . 15464 1 114 . 1 1 17 17 GLU HG3 H 1 2.347 0.02 . 2 . . . . 17 GLU HG3 . 15464 1 115 . 1 1 18 18 ASN H H 1 7.418 0.02 . 1 . . . . 18 ASN H . 15464 1 116 . 1 1 18 18 ASN HA H 1 4.436 0.02 . 1 . . . . 18 ASN HA . 15464 1 117 . 1 1 18 18 ASN HB2 H 1 2.577 0.02 . 2 . . . . 18 ASN HB2 . 15464 1 118 . 1 1 18 18 ASN HB3 H 1 2.499 0.02 . 2 . . . . 18 ASN HB3 . 15464 1 119 . 1 1 18 18 ASN HD21 H 1 6.381 0.02 . 2 . . . . 18 ASN HD21 . 15464 1 120 . 1 1 18 18 ASN HD22 H 1 7.111 0.02 . 2 . . . . 18 ASN HD22 . 15464 1 121 . 1 1 19 19 TYR H H 1 7.862 0.02 . 1 . . . . 19 TYR H . 15464 1 122 . 1 1 19 19 TYR HA H 1 4.426 0.02 . 1 . . . . 19 TYR HA . 15464 1 123 . 1 1 19 19 TYR HB2 H 1 2.944 0.02 . 1 . . . . 19 TYR HB2 . 15464 1 124 . 1 1 19 19 TYR HB3 H 1 3.301 0.02 . 1 . . . . 19 TYR HB3 . 15464 1 125 . 1 1 19 19 TYR HD1 H 1 7.284 0.02 . 3 . . . . 19 TYR HD1 . 15464 1 126 . 1 1 19 19 TYR HE1 H 1 6.738 0.02 . 3 . . . . 19 TYR HE1 . 15464 1 127 . 1 1 20 20 CYS H H 1 7.393 0.02 . 1 . . . . 20 CYS H . 15464 1 128 . 1 1 20 20 CYS HA H 1 4.736 0.02 . 1 . . . . 20 CYS HA . 15464 1 129 . 1 1 20 20 CYS HB2 H 1 3.209 0.02 . 2 . . . . 20 CYS HB2 . 15464 1 130 . 1 1 20 20 CYS HB3 H 1 2.813 0.02 . 2 . . . . 20 CYS HB3 . 15464 1 131 . 1 1 21 21 ASN H H 1 7.943 0.02 . 1 . . . . 21 ASN H . 15464 1 132 . 1 1 21 21 ASN HA H 1 4.602 0.02 . 1 . . . . 21 ASN HA . 15464 1 133 . 1 1 21 21 ASN HB2 H 1 2.793 0.02 . 2 . . . . 21 ASN HB2 . 15464 1 134 . 1 1 21 21 ASN HB3 H 1 2.682 0.02 . 2 . . . . 21 ASN HB3 . 15464 1 135 . 1 1 21 21 ASN HD21 H 1 6.564 0.02 . 2 . . . . 21 ASN HD21 . 15464 1 136 . 1 1 21 21 ASN HD22 H 1 7.386 0.02 . 2 . . . . 21 ASN HD22 . 15464 1 137 . 2 2 1 1 PHE HA H 1 4.270 0.02 . 1 . . . . 1 PHE HA . 15464 1 138 . 2 2 1 1 PHE HB2 H 1 3.193 0.02 . 2 . . . . 1 PHE HB2 . 15464 1 139 . 2 2 1 1 PHE HB3 H 1 3.141 0.02 . 2 . . . . 1 PHE HB3 . 15464 1 140 . 2 2 1 1 PHE HD1 H 1 7.262 0.02 . 3 . . . . 1 PHE HD1 . 15464 1 141 . 2 2 1 1 PHE HE1 H 1 7.383 0.02 . 3 . . . . 1 PHE HE1 . 15464 1 142 . 2 2 2 2 VAL H H 1 8.083 0.02 . 1 . . . . 2 VAL H . 15464 1 143 . 2 2 2 2 VAL HA H 1 4.100 0.02 . 1 . . . . 2 VAL HA . 15464 1 144 . 2 2 2 2 VAL HB H 1 1.959 0.02 . 1 . . . . 2 VAL HB . 15464 1 145 . 2 2 2 2 VAL HG11 H 1 0.876 0.02 . 1 . . . . 2 VAL HG1 . 15464 1 146 . 2 2 2 2 VAL HG12 H 1 0.876 0.02 . 1 . . . . 2 VAL HG1 . 15464 1 147 . 2 2 2 2 VAL HG13 H 1 0.876 0.02 . 1 . . . . 2 VAL HG1 . 15464 1 148 . 2 2 2 2 VAL HG21 H 1 0.876 0.02 . 1 . . . . 2 VAL HG2 . 15464 1 149 . 2 2 2 2 VAL HG22 H 1 0.876 0.02 . 1 . . . . 2 VAL HG2 . 15464 1 150 . 2 2 2 2 VAL HG23 H 1 0.876 0.02 . 1 . . . . 2 VAL HG2 . 15464 1 151 . 2 2 3 3 ASN H H 1 8.239 0.02 . 1 . . . . 3 ASN H . 15464 1 152 . 2 2 3 3 ASN HA H 1 4.638 0.02 . 1 . . . . 3 ASN HA . 15464 1 153 . 2 2 3 3 ASN HB2 H 1 2.763 0.02 . 2 . . . . 3 ASN HB2 . 15464 1 154 . 2 2 3 3 ASN HB3 H 1 2.700 0.02 . 2 . . . . 3 ASN HB3 . 15464 1 155 . 2 2 3 3 ASN HD21 H 1 6.760 0.02 . 2 . . . . 3 ASN HD21 . 15464 1 156 . 2 2 3 3 ASN HD22 H 1 7.445 0.02 . 2 . . . . 3 ASN HD22 . 15464 1 157 . 2 2 4 4 GLN H H 1 8.181 0.02 . 1 . . . . 4 GLN H . 15464 1 158 . 2 2 4 4 GLN HA H 1 4.373 0.02 . 1 . . . . 4 GLN HA . 15464 1 159 . 2 2 4 4 GLN HB2 H 1 2.088 0.02 . 2 . . . . 4 GLN HB2 . 15464 1 160 . 2 2 4 4 GLN HB3 H 1 1.818 0.02 . 2 . . . . 4 GLN HB3 . 15464 1 161 . 2 2 4 4 GLN HE21 H 1 6.619 0.02 . 2 . . . . 4 GLN HE21 . 15464 1 162 . 2 2 4 4 GLN HE22 H 1 7.314 0.02 . 2 . . . . 4 GLN HE22 . 15464 1 163 . 2 2 4 4 GLN HG2 H 1 2.231 0.02 . 2 . . . . 4 GLN HG2 . 15464 1 164 . 2 2 4 4 GLN HG3 H 1 2.190 0.02 . 2 . . . . 4 GLN HG3 . 15464 1 165 . 2 2 5 5 HIS H H 1 8.379 0.02 . 1 . . . . 5 HIS H . 15464 1 166 . 2 2 5 5 HIS HA H 1 4.461 0.02 . 1 . . . . 5 HIS HA . 15464 1 167 . 2 2 5 5 HIS HB2 H 1 3.233 0.02 . 1 . . . . 5 HIS HB2 . 15464 1 168 . 2 2 5 5 HIS HB3 H 1 3.528 0.02 . 1 . . . . 5 HIS HB3 . 15464 1 169 . 2 2 5 5 HIS HD1 H 1 7.360 0.02 . 1 . . . . 5 HIS HD1 . 15464 1 170 . 2 2 5 5 HIS HD2 H 1 7.360 0.02 . 1 . . . . 5 HIS HD2 . 15464 1 171 . 2 2 5 5 HIS HE1 H 1 8.496 0.02 . 1 . . . . 5 HIS HE1 . 15464 1 172 . 2 2 6 6 LEU H H 1 8.754 0.02 . 1 . . . . 6 LEU H . 15464 1 173 . 2 2 6 6 LEU HA H 1 4.454 0.02 . 1 . . . . 6 LEU HA . 15464 1 174 . 2 2 6 6 LEU HB2 H 1 1.688 0.02 . 1 . . . . 6 LEU HB2 . 15464 1 175 . 2 2 6 6 LEU HB3 H 1 1.006 0.02 . 1 . . . . 6 LEU HB3 . 15464 1 176 . 2 2 6 6 LEU HD11 H 1 0.848 0.02 . 2 . . . . 6 LEU HD1 . 15464 1 177 . 2 2 6 6 LEU HD12 H 1 0.848 0.02 . 2 . . . . 6 LEU HD1 . 15464 1 178 . 2 2 6 6 LEU HD13 H 1 0.848 0.02 . 2 . . . . 6 LEU HD1 . 15464 1 179 . 2 2 6 6 LEU HD21 H 1 0.740 0.02 . 2 . . . . 6 LEU HD2 . 15464 1 180 . 2 2 6 6 LEU HD22 H 1 0.740 0.02 . 2 . . . . 6 LEU HD2 . 15464 1 181 . 2 2 6 6 LEU HD23 H 1 0.740 0.02 . 2 . . . . 6 LEU HD2 . 15464 1 182 . 2 2 6 6 LEU HG H 1 1.551 0.02 . 1 . . . . 6 LEU HG . 15464 1 183 . 2 2 7 7 CYS H H 1 8.153 0.02 . 1 . . . . 7 CYS H . 15464 1 184 . 2 2 7 7 CYS HA H 1 4.869 0.02 . 1 . . . . 7 CYS HA . 15464 1 185 . 2 2 7 7 CYS HB2 H 1 3.186 0.02 . 1 . . . . 7 CYS HB2 . 15464 1 186 . 2 2 7 7 CYS HB3 H 1 2.957 0.02 . 1 . . . . 7 CYS HB3 . 15464 1 187 . 2 2 8 8 GLY H H 1 8.852 0.02 . 1 . . . . 8 GLY H . 15464 1 188 . 2 2 8 8 GLY HA2 H 1 3.967 0.02 . 2 . . . . 8 GLY HA2 . 15464 1 189 . 2 2 8 8 GLY HA3 H 1 3.783 0.02 . 2 . . . . 8 GLY HA3 . 15464 1 190 . 2 2 9 9 SER H H 1 8.829 0.02 . 1 . . . . 9 SER H . 15464 1 191 . 2 2 9 9 SER HA H 1 4.075 0.02 . 1 . . . . 9 SER HA . 15464 1 192 . 2 2 9 9 SER HB2 H 1 3.844 0.02 . 1 . . . . 9 SER HB2 . 15464 1 193 . 2 2 9 9 SER HB3 H 1 3.844 0.02 . 1 . . . . 9 SER HB3 . 15464 1 194 . 2 2 10 10 HIS H H 1 7.937 0.02 . 1 . . . . 10 HIS H . 15464 1 195 . 2 2 10 10 HIS HA H 1 4.490 0.02 . 1 . . . . 10 HIS HA . 15464 1 196 . 2 2 10 10 HIS HB2 H 1 3.497 0.02 . 1 . . . . 10 HIS HB2 . 15464 1 197 . 2 2 10 10 HIS HB3 H 1 3.262 0.02 . 1 . . . . 10 HIS HB3 . 15464 1 198 . 2 2 10 10 HIS HD1 H 1 7.422 0.02 . 1 . . . . 10 HIS HD1 . 15464 1 199 . 2 2 10 10 HIS HD2 H 1 7.422 0.02 . 1 . . . . 10 HIS HD2 . 15464 1 200 . 2 2 10 10 HIS HE1 H 1 8.626 0.02 . 1 . . . . 10 HIS HE1 . 15464 1 201 . 2 2 11 11 LEU H H 1 7.126 0.02 . 1 . . . . 11 LEU H . 15464 1 202 . 2 2 11 11 LEU HA H 1 3.992 0.02 . 1 . . . . 11 LEU HA . 15464 1 203 . 2 2 11 11 LEU HB2 H 1 1.852 0.02 . 2 . . . . 11 LEU HB2 . 15464 1 204 . 2 2 11 11 LEU HB3 H 1 1.241 0.02 . 2 . . . . 11 LEU HB3 . 15464 1 205 . 2 2 11 11 LEU HD11 H 1 0.803 0.02 . 2 . . . . 11 LEU HD1 . 15464 1 206 . 2 2 11 11 LEU HD12 H 1 0.803 0.02 . 2 . . . . 11 LEU HD1 . 15464 1 207 . 2 2 11 11 LEU HD13 H 1 0.803 0.02 . 2 . . . . 11 LEU HD1 . 15464 1 208 . 2 2 11 11 LEU HD21 H 1 0.752 0.02 . 2 . . . . 11 LEU HD2 . 15464 1 209 . 2 2 11 11 LEU HD22 H 1 0.752 0.02 . 2 . . . . 11 LEU HD2 . 15464 1 210 . 2 2 11 11 LEU HD23 H 1 0.752 0.02 . 2 . . . . 11 LEU HD2 . 15464 1 211 . 2 2 11 11 LEU HG H 1 1.374 0.02 . 1 . . . . 11 LEU HG . 15464 1 212 . 2 2 12 12 VAL H H 1 7.284 0.02 . 1 . . . . 12 VAL H . 15464 1 213 . 2 2 12 12 VAL HA H 1 3.392 0.02 . 1 . . . . 12 VAL HA . 15464 1 214 . 2 2 12 12 VAL HB H 1 2.054 0.02 . 1 . . . . 12 VAL HB . 15464 1 215 . 2 2 12 12 VAL HG11 H 1 0.960 0.02 . 2 . . . . 12 VAL HG1 . 15464 1 216 . 2 2 12 12 VAL HG12 H 1 0.960 0.02 . 2 . . . . 12 VAL HG1 . 15464 1 217 . 2 2 12 12 VAL HG13 H 1 0.960 0.02 . 2 . . . . 12 VAL HG1 . 15464 1 218 . 2 2 12 12 VAL HG21 H 1 0.923 0.02 . 2 . . . . 12 VAL HG2 . 15464 1 219 . 2 2 12 12 VAL HG22 H 1 0.923 0.02 . 2 . . . . 12 VAL HG2 . 15464 1 220 . 2 2 12 12 VAL HG23 H 1 0.923 0.02 . 2 . . . . 12 VAL HG2 . 15464 1 221 . 2 2 13 13 GLU H H 1 7.921 0.02 . 1 . . . . 13 GLU H . 15464 1 222 . 2 2 13 13 GLU HA H 1 4.053 0.02 . 1 . . . . 13 GLU HA . 15464 1 223 . 2 2 13 13 GLU HB2 H 1 2.139 0.02 . 2 . . . . 13 GLU HB2 . 15464 1 224 . 2 2 13 13 GLU HB3 H 1 2.070 0.02 . 2 . . . . 13 GLU HB3 . 15464 1 225 . 2 2 13 13 GLU HG2 H 1 2.516 0.02 . 1 . . . . 13 GLU HG2 . 15464 1 226 . 2 2 13 13 GLU HG3 H 1 2.516 0.02 . 1 . . . . 13 GLU HG3 . 15464 1 227 . 2 2 14 14 ALA H H 1 7.755 0.02 . 1 . . . . 14 ALA H . 15464 1 228 . 2 2 14 14 ALA HA H 1 4.055 0.02 . 1 . . . . 14 ALA HA . 15464 1 229 . 2 2 14 14 ALA HB1 H 1 1.446 0.02 . 1 . . . . 14 ALA HB . 15464 1 230 . 2 2 14 14 ALA HB2 H 1 1.446 0.02 . 1 . . . . 14 ALA HB . 15464 1 231 . 2 2 14 14 ALA HB3 H 1 1.446 0.02 . 1 . . . . 14 ALA HB . 15464 1 232 . 2 2 15 15 LEU H H 1 8.072 0.02 . 1 . . . . 15 LEU H . 15464 1 233 . 2 2 15 15 LEU HA H 1 3.915 0.02 . 1 . . . . 15 LEU HA . 15464 1 234 . 2 2 15 15 LEU HB2 H 1 1.528 0.02 . 2 . . . . 15 LEU HB2 . 15464 1 235 . 2 2 15 15 LEU HB3 H 1 1.140 0.02 . 2 . . . . 15 LEU HB3 . 15464 1 236 . 2 2 15 15 LEU HD11 H 1 0.702 0.02 . 2 . . . . 15 LEU HD1 . 15464 1 237 . 2 2 15 15 LEU HD12 H 1 0.702 0.02 . 2 . . . . 15 LEU HD1 . 15464 1 238 . 2 2 15 15 LEU HD13 H 1 0.702 0.02 . 2 . . . . 15 LEU HD1 . 15464 1 239 . 2 2 15 15 LEU HD21 H 1 0.589 0.02 . 2 . . . . 15 LEU HD2 . 15464 1 240 . 2 2 15 15 LEU HD22 H 1 0.589 0.02 . 2 . . . . 15 LEU HD2 . 15464 1 241 . 2 2 15 15 LEU HD23 H 1 0.589 0.02 . 2 . . . . 15 LEU HD2 . 15464 1 242 . 2 2 15 15 LEU HG H 1 1.527 0.02 . 1 . . . . 15 LEU HG . 15464 1 243 . 2 2 16 16 TYR H H 1 8.149 0.02 . 1 . . . . 16 TYR H . 15464 1 244 . 2 2 16 16 TYR HA H 1 4.187 0.02 . 1 . . . . 16 TYR HA . 15464 1 245 . 2 2 16 16 TYR HB2 H 1 3.109 0.02 . 2 . . . . 16 TYR HB2 . 15464 1 246 . 2 2 16 16 TYR HB3 H 1 3.109 0.02 . 2 . . . . 16 TYR HB3 . 15464 1 247 . 2 2 16 16 TYR HD1 H 1 7.100 0.02 . 3 . . . . 16 TYR HD1 . 15464 1 248 . 2 2 16 16 TYR HE1 H 1 6.742 0.02 . 3 . . . . 16 TYR HE1 . 15464 1 249 . 2 2 17 17 LEU H H 1 7.918 0.02 . 1 . . . . 17 LEU H . 15464 1 250 . 2 2 17 17 LEU HA H 1 4.054 0.02 . 1 . . . . 17 LEU HA . 15464 1 251 . 2 2 17 17 LEU HB2 H 1 1.887 0.02 . 2 . . . . 17 LEU HB2 . 15464 1 252 . 2 2 17 17 LEU HB3 H 1 1.618 0.02 . 2 . . . . 17 LEU HB3 . 15464 1 253 . 2 2 17 17 LEU HD11 H 1 0.938 0.02 . 2 . . . . 17 LEU HD1 . 15464 1 254 . 2 2 17 17 LEU HD12 H 1 0.938 0.02 . 2 . . . . 17 LEU HD1 . 15464 1 255 . 2 2 17 17 LEU HD13 H 1 0.938 0.02 . 2 . . . . 17 LEU HD1 . 15464 1 256 . 2 2 17 17 LEU HD21 H 1 0.916 0.02 . 2 . . . . 17 LEU HD2 . 15464 1 257 . 2 2 17 17 LEU HD22 H 1 0.916 0.02 . 2 . . . . 17 LEU HD2 . 15464 1 258 . 2 2 17 17 LEU HD23 H 1 0.916 0.02 . 2 . . . . 17 LEU HD2 . 15464 1 259 . 2 2 17 17 LEU HG H 1 1.868 0.02 . 1 . . . . 17 LEU HG . 15464 1 260 . 2 2 18 18 VAL H H 1 8.414 0.02 . 1 . . . . 18 VAL H . 15464 1 261 . 2 2 18 18 VAL HA H 1 3.823 0.02 . 1 . . . . 18 VAL HA . 15464 1 262 . 2 2 18 18 VAL HB H 1 2.093 0.02 . 1 . . . . 18 VAL HB . 15464 1 263 . 2 2 18 18 VAL HG11 H 1 1.012 0.02 . 2 . . . . 18 VAL HG1 . 15464 1 264 . 2 2 18 18 VAL HG12 H 1 1.012 0.02 . 2 . . . . 18 VAL HG1 . 15464 1 265 . 2 2 18 18 VAL HG13 H 1 1.012 0.02 . 2 . . . . 18 VAL HG1 . 15464 1 266 . 2 2 18 18 VAL HG21 H 1 0.876 0.02 . 2 . . . . 18 VAL HG2 . 15464 1 267 . 2 2 18 18 VAL HG22 H 1 0.876 0.02 . 2 . . . . 18 VAL HG2 . 15464 1 268 . 2 2 18 18 VAL HG23 H 1 0.876 0.02 . 2 . . . . 18 VAL HG2 . 15464 1 269 . 2 2 19 19 CYS H H 1 8.606 0.02 . 1 . . . . 19 CYS H . 15464 1 270 . 2 2 19 19 CYS HA H 1 4.718 0.02 . 1 . . . . 19 CYS HA . 15464 1 271 . 2 2 19 19 CYS HB2 H 1 2.908 0.02 . 1 . . . . 19 CYS HB2 . 15464 1 272 . 2 2 19 19 CYS HB3 H 1 3.207 0.02 . 1 . . . . 19 CYS HB3 . 15464 1 273 . 2 2 20 20 GLY H H 1 7.807 0.02 . 1 . . . . 20 GLY H . 15464 1 274 . 2 2 20 20 GLY HA2 H 1 3.877 0.02 . 1 . . . . 20 GLY HA2 . 15464 1 275 . 2 2 20 20 GLY HA3 H 1 3.877 0.02 . 1 . . . . 20 GLY HA3 . 15464 1 276 . 2 2 21 21 GLU H H 1 8.147 0.02 . 1 . . . . 21 GLU H . 15464 1 277 . 2 2 21 21 GLU HA H 1 4.216 0.02 . 1 . . . . 21 GLU HA . 15464 1 278 . 2 2 21 21 GLU HB2 H 1 2.159 0.02 . 2 . . . . 21 GLU HB2 . 15464 1 279 . 2 2 21 21 GLU HB3 H 1 2.070 0.02 . 2 . . . . 21 GLU HB3 . 15464 1 280 . 2 2 21 21 GLU HG2 H 1 2.470 0.02 . 1 . . . . 21 GLU HG2 . 15464 1 281 . 2 2 21 21 GLU HG3 H 1 2.470 0.02 . 1 . . . . 21 GLU HG3 . 15464 1 282 . 2 2 22 22 ARG H H 1 7.835 0.02 . 1 . . . . 22 ARG H . 15464 1 283 . 2 2 22 22 ARG HA H 1 4.190 0.02 . 1 . . . . 22 ARG HA . 15464 1 284 . 2 2 22 22 ARG HB2 H 1 1.937 0.02 . 2 . . . . 22 ARG HB2 . 15464 1 285 . 2 2 22 22 ARG HB3 H 1 1.877 0.02 . 2 . . . . 22 ARG HB3 . 15464 1 286 . 2 2 22 22 ARG HD2 H 1 3.209 0.02 . 1 . . . . 22 ARG HD2 . 15464 1 287 . 2 2 22 22 ARG HD3 H 1 3.209 0.02 . 1 . . . . 22 ARG HD3 . 15464 1 288 . 2 2 22 22 ARG HE H 1 7.221 0.02 . 1 . . . . 22 ARG HE . 15464 1 289 . 2 2 22 22 ARG HG2 H 1 1.713 0.02 . 1 . . . . 22 ARG HG2 . 15464 1 290 . 2 2 22 22 ARG HG3 H 1 1.713 0.02 . 1 . . . . 22 ARG HG3 . 15464 1 291 . 2 2 23 23 GLY H H 1 7.757 0.02 . 1 . . . . 23 GLY H . 15464 1 292 . 2 2 23 23 GLY HA2 H 1 3.882 0.02 . 2 . . . . 23 GLY HA2 . 15464 1 293 . 2 2 23 23 GLY HA3 H 1 3.814 0.02 . 2 . . . . 23 GLY HA3 . 15464 1 294 . 2 2 24 24 PHE H H 1 7.648 0.02 . 1 . . . . 24 PHE H . 15464 1 295 . 2 2 24 24 PHE HA H 1 4.667 0.02 . 1 . . . . 24 PHE HA . 15464 1 296 . 2 2 24 24 PHE HB2 H 1 3.031 0.02 . 2 . . . . 24 PHE HB2 . 15464 1 297 . 2 2 24 24 PHE HB3 H 1 2.885 0.02 . 2 . . . . 24 PHE HB3 . 15464 1 298 . 2 2 24 24 PHE HD1 H 1 7.002 0.02 . 3 . . . . 24 PHE HD1 . 15464 1 299 . 2 2 24 24 PHE HE1 H 1 7.151 0.02 . 3 . . . . 24 PHE HE1 . 15464 1 300 . 2 2 25 25 PHE H H 1 8.006 0.02 . 1 . . . . 25 PHE H . 15464 1 301 . 2 2 25 25 PHE HA H 1 4.588 0.02 . 1 . . . . 25 PHE HA . 15464 1 302 . 2 2 25 25 PHE HB2 H 1 3.075 0.02 . 2 . . . . 25 PHE HB2 . 15464 1 303 . 2 2 25 25 PHE HB3 H 1 2.956 0.02 . 2 . . . . 25 PHE HB3 . 15464 1 304 . 2 2 25 25 PHE HD1 H 1 7.196 0.02 . 3 . . . . 25 PHE HD1 . 15464 1 305 . 2 2 25 25 PHE HE1 H 1 7.287 0.02 . 3 . . . . 25 PHE HE1 . 15464 1 306 . 2 2 26 26 TYR H H 1 7.766 0.02 . 1 . . . . 26 TYR H . 15464 1 307 . 2 2 26 26 TYR HA H 1 4.582 0.02 . 1 . . . . 26 TYR HA . 15464 1 308 . 2 2 26 26 TYR HB2 H 1 2.948 0.02 . 2 . . . . 26 TYR HB2 . 15464 1 309 . 2 2 26 26 TYR HB3 H 1 2.907 0.02 . 2 . . . . 26 TYR HB3 . 15464 1 310 . 2 2 26 26 TYR HD1 H 1 7.034 0.02 . 3 . . . . 26 TYR HD1 . 15464 1 311 . 2 2 26 26 TYR HE1 H 1 6.755 0.02 . 3 . . . . 26 TYR HE1 . 15464 1 312 . 2 2 27 27 THR H H 1 7.644 0.02 . 1 . . . . 27 THR H . 15464 1 313 . 2 2 27 27 THR HA H 1 4.551 0.02 . 1 . . . . 27 THR HA . 15464 1 314 . 2 2 27 27 THR HB H 1 4.064 0.02 . 1 . . . . 27 THR HB . 15464 1 315 . 2 2 27 27 THR HG21 H 1 1.171 0.02 . 1 . . . . 27 THR HG2 . 15464 1 316 . 2 2 27 27 THR HG22 H 1 1.171 0.02 . 1 . . . . 27 THR HG2 . 15464 1 317 . 2 2 27 27 THR HG23 H 1 1.171 0.02 . 1 . . . . 27 THR HG2 . 15464 1 318 . 2 2 28 28 PRO HA H 1 4.334 0.02 . 1 . . . . 28 PRO HA . 15464 1 319 . 2 2 28 28 PRO HB2 H 1 2.232 0.02 . 2 . . . . 28 PRO HB2 . 15464 1 320 . 2 2 28 28 PRO HB3 H 1 1.921 0.02 . 2 . . . . 28 PRO HB3 . 15464 1 321 . 2 2 28 28 PRO HD2 H 1 3.646 0.02 . 1 . . . . 28 PRO HD2 . 15464 1 322 . 2 2 28 28 PRO HD3 H 1 3.646 0.02 . 1 . . . . 28 PRO HD3 . 15464 1 323 . 2 2 28 28 PRO HG2 H 1 1.994 0.02 . 2 . . . . 28 PRO HG2 . 15464 1 324 . 2 2 28 28 PRO HG3 H 1 1.915 0.02 . 2 . . . . 28 PRO HG3 . 15464 1 325 . 2 2 29 29 LYS HA H 1 4.358 0.02 . 1 . . . . 29 LYS HA . 15464 1 326 . 2 2 29 29 LYS HB2 H 1 1.852 0.02 . 2 . . . . 29 LYS HB2 . 15464 1 327 . 2 2 29 29 LYS HB3 H 1 1.734 0.02 . 2 . . . . 29 LYS HB3 . 15464 1 328 . 2 2 29 29 LYS HD2 H 1 1.656 0.02 . 1 . . . . 29 LYS HD2 . 15464 1 329 . 2 2 29 29 LYS HD3 H 1 1.656 0.02 . 1 . . . . 29 LYS HD3 . 15464 1 330 . 2 2 29 29 LYS HE2 H 1 2.950 0.02 . 1 . . . . 29 LYS HE2 . 15464 1 331 . 2 2 29 29 LYS HE3 H 1 2.950 0.02 . 1 . . . . 29 LYS HE3 . 15464 1 332 . 2 2 29 29 LYS HG2 H 1 1.449 0.02 . 1 . . . . 29 LYS HG2 . 15464 1 333 . 2 2 29 29 LYS HG3 H 1 1.449 0.02 . 1 . . . . 29 LYS HG3 . 15464 1 334 . 2 2 30 30 THR H H 1 7.726 0.02 . 1 . . . . 30 THR H . 15464 1 335 . 2 2 30 30 THR HA H 1 4.309 0.02 . 1 . . . . 30 THR HA . 15464 1 336 . 2 2 30 30 THR HB H 1 4.292 0.02 . 1 . . . . 30 THR HB . 15464 1 337 . 2 2 30 30 THR HG21 H 1 1.152 0.02 . 1 . . . . 30 THR HG2 . 15464 1 338 . 2 2 30 30 THR HG22 H 1 1.152 0.02 . 1 . . . . 30 THR HG2 . 15464 1 339 . 2 2 30 30 THR HG23 H 1 1.152 0.02 . 1 . . . . 30 THR HG2 . 15464 1 stop_ save_